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Sub-clinical detection methods in multiple sclerosis
Visually symptomatic multiple sclerosis (MS) provides only part of the required information to assist in understanding the disease. Recently, researchers have concentrated their efforts on diagnosing MS cases in the subclinical period. The aim of this paper was to assess...
Internal limiting membrane (ILM) peeling on blood flow in diabetic macula
This is a retrospective review of notes for diabetic patients with epiretinal membrane (ERM) who underwent surgery by the same surgeon. Nineteen had ERM peeling only, while the remaining 18 had both ERM and internal limiting membrane (ILM) peeling. The...
Inverted internal limiting membrane flap vs internal limiting membrane insertion technique for large macular holes
This meta-analysis aimed to compare and evaluate the morphological and functional outcomes between the inverted internal limiting membrane (ILM) flap and ILM insertion techniques in the treatment of large macular holes (MHs). The primary outcome measures were defined by the...
Transcriptomic and regulatory gene associations in open angle glaucoma
The authors report a study utilising a publicly available whole exome sequencing dataset of 28 patients with primary open angle glaucoma (POAG) and seven healthy control patients, and a transcriptomic dataset from the trabecular meshwork of four POAG patients and...
Ocular surface and meibomian gland changes in cicatricial conjunctival disease
The authors evaluate long-term structural and functional meibomian gland and lid margin changes in a retrospective study of 64 patients (64 eyes) with chronic cicatricial conjunctival diseases (CCDs), including ocular cicatricial pemphigoid (OCP; n=22), Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS-TEN; n=24),...
Emergency eye care in the UK: the way forward?
In this paper the authors highlight issues pertaining to the growing number of patients presenting to the emergency eye services in the UK. Data collection involved literature review, telephone surveys and email correspondence (n=142). Ninety-one lead clinicians responded and a...The work of RNIB and ECLOs
With more than 2,000,000 people in the UK living with some degree of sight loss and over 300,000 registered as blind or partially sighted, it is important for anyone living with sight loss to know they’re not alone. At what...Ocular manifestations of multiple sclerosis: an overview
Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system (CNS), in which there is dissemination of lesions in time (two or more clinical events) and space (multiple lesions seen on brain and spinal imaging). The pathophysiology...
