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Medical treatment of orbital lymphatic malformations

This is a literature review of the use of Sirolimus, to treat orbital lymphatic malformations. Sirolimus is an immunosuppressant used in renal transplants, and acts by inhibiting mammalian target of rapamycin (mTOR), which in turn inhibits activation of T and...

Rituximab efficacy for juvenile idiopathic arthritis

This is a retrospective study about the long-term efficacy of rituximab in patients with severe juvenile idiopathic arthritis (JIA)-associated uveitis. A total of eight patients (15 eyes) were recruited in this study in a single tertiary referral centre from Italy....

Trabeculectomy with MMC in post-traumatic angle recession glaucoma

This study aimed to evaluate the outcomes of primary trabeculectomy with mitomycin-C (trab MMC) in phakic eyes with post-traumatic angle recession glaucoma with no prior intraocular surgery. Thirty-two phakic eyes of 32 patients who underwent trab MMC between January-2002 and...

Is intracranial pressure affected by the valsalva manoeuvres and exercise?

Idiopathic intracranial hypertension (IIH) is characterised by elevated intracranial pressure (ICP), which leads to optic nerve head swelling and a risk of visual loss. The impact of straining and exercise on ICP regulation is poorly understood yet clinically relevant to...

Identifying life-threatening uveal melanoma: A directed application of general-purpose AI

Uveal melanoma (UM) is a rare but aggressive eye cancer, affecting approximately six people per million annually [1]. Uveal melanoma arises in three locations: the choroid, ciliary body, and iris. As the most common primary intraocular malignancy in adults, UM...

Air tamponade in pars plana vitrectomy for primary rhegmatogenous retinal detachment repair

The authors report a study aimed to establish the use of air as a tamponade agent for primary rhegmatogenous retinal detachment (RRD) treatment, regardless of the position or the number of retinal breaks. Two hundred and thirty-six eyes of 230...

Postgraduate training for ophthalmic practitioners

The UK currently spends £25 billion per year on ocular disease, and there is expected to be a 40% increase in those affected by visual impairment by 2050 [1]. To manage this demand, 82% of ophthalmology units across the UK...

Katherine McVeigh

In this new section we profile creatives whose work is inspired by the eye. Since I was a child, I have enjoyed art projects. It provided me with a space for creative freedom without rules or restrictions. Unfortunately, this fell...

Implementing technology to improve global eye health

Technological innovation is providing new solutions to transform global eye health [1–5]. In particular, research towards the development of artificial intelligence (AI) tools in ophthalmology has gained pace in recent years. However, there has been little research relating to its...

Feb/Mar 2014 Quiz 2

History A 65-year-old lady presented with a ten year history of nonspecific visual disturbance and mild symptoms of dry eyes. Questioning revealed progressive nyctalopia. Previous medical history of note included Crohn’s disease requiring two bowel resections including small intestine. Figure...

The flexibility of virtual clinics

Virtual clinics in ophthalmology are typically associated with glaucoma and medical retina, where they are now a well-established part of the landscape. The availability of an ophthalmic electronic patient record (EPR) makes the deployment and management of virtual clinics much...

Glaucoma medications and ocular surface disease

This literature review examined ocular surface disease (OSD) associated with glaucoma medication. The authors examined the prevalence of features and management guidelines glaucoma medication associated OSD. Fifty-eight articles published within the past five years are included in this review and...