You searched for "tear"
Ocular damage from laser pointers
This retrospective study of case notes from a tertiary eye centre over a five-year period, recruited nine children (12 eyes: eight boys) aged 9-15 years. Three presented with deteriorating vision whilst others had retinal changes noted as incidental findings at...
Surgical management and review of congenital inferior rectus dysgenesis
Three cases are presented of congenital inferior rectus (IR) dysgenesis causing hypertropia. Case 1 was a two-year-old female with intermittent vertical strabismus of 20PD and -2 limitation on depression, worse in abduction. MRI imaging showed a hypoplastic IR. Following surgery,...
Brolucizumab in age-related macular degeneration, HAWK Study
The aim of the study was to collect additional data on efficacy and safety of brolucizumab 6mg intended for commercialization in age-related macular degeneration (AMD) (with an increase in pH and decrease in polysorbate concentration). The HAWK Study was a...
Ophthalmic presentations and outcomes in Erdheim-Chester disease
This is a comprehensive article describing clinical manifestations and pathogenesis of Erdheim-Chester disease (ECD) followed by a literature review of the available treatments. The authors look to compare historical treatment (HT) with vemurafenib, a BRAF inhibitor. ECD is a non-Langerhans...
Acute comitant esotropia as the presenting sign of diffuse intrinsic pontine glioma
The authors present four children with acute comitant esotropia (AACE) associated with diffuse intrinsic pontine glioma. All were treated with radiation therapy and all subsequently died due to the tumour. Children were aged 5, 5, 4.5 and 11 years. General...
Aquaporin-4 antibody testing in isolate optic neuritis
The authors present a retrospective case review of first presentation isolated cases of optic neuritis tested for aquaporin-4 antibody across two centres over a nine-year period. Exclusion criteria included known diagnosis or other manifestations of neuromyelitis optica spectrum disorder. Two...
Natural history of optic nerve head drusen in a paediatric population
A retrospective case notes review is presented focusing on children diagnosed with optic nerve head drusen over an eight-year period. Inclusion criteria included cases coded for optic nerve head drusen and / or pseudopapilledema. The aim of the study was...
Ophthalmic findings following noticeable external injury following forceps delivery
This study prospectively recruited consecutive women following a forceps vaginal delivery of a single foetus in cephalic position over a two-year period. Individual patient consent was waived by the approving body. The neonates received a paediatrician assessment soon after birth....
Features and outcomes of pulled-in-two syndrome
Pulled-in-two (PIT) syndrome is a sudden rupture of the extraocular muscle during strabismus surgery, typically with minimal tension intraoperatively without excessive force. This is a rare occurrence and this study reports cases from a single centre over a seven-year period....
Persistent subretinal fluid (PSFF) in pneumatic retinopexy (PNR) versus pars plana vitrectomy (PPV) for rhegmatogenous retinal detachment (RRD): posthoc analysis of the PIVOT randomised trial
This is a posthoc study of the PIVOT randomised trial over a 12 month period, to evaluate the functional outcomes of the incidence of PSF in PnR versus PPV following RRD surgery. One hundred and fifty-eight patients were recruited and...
Long-term outcomes of deep anterior lamellar versus penetrating keratoplasty for keratoconus
This is a retrospective consecutive and comparative case series of keratoplasties (228 deep anterior lamellar keratoplasties (DALKs) and 274 penetrating keratoplasties (PKs)) in a single centre by one surgeon in France, between 1993 and 2021. Graft survival was 96.7% at...
