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2443 results found

Mapping areas to target location of vision screening services

In this study, the authors analysed data from a community vision screening program to determine the efficiency of vision screening in reaching lower income populations. The study used ArcGIS (Esri) mapping software to develop a visual representation of areas needing...

Features of childhood cases of sixth nerve palsy

Based on limited information available for cranial nerve palsies in children, the authors aimed to collect data on new onset paediatric sixth nerve palsies in a UK population. This was a retrospective study over 10 years for children aged <18...

Assessing possibility of deferring lumbar puncture in mild idiopathic intracranial hypertension

This was a retrospective review of patients consecutively presenting with idiopathic intracranial hypertension (IIH) to a tertiary neuro-ophthalmology clinic without a lumbar puncture (LP) over an eight-year period. Inclusion criteria included true optic disc oedema, retinal nerve layer thickness ≤300µm,...

Ocular damage from laser pointers

This retrospective study of case notes from a tertiary eye centre over a five-year period, recruited nine children (12 eyes: eight boys) aged 9-15 years. Three presented with deteriorating vision whilst others had retinal changes noted as incidental findings at...

Surgical management and review of congenital inferior rectus dysgenesis

Three cases are presented of congenital inferior rectus (IR) dysgenesis causing hypertropia. Case 1 was a two-year-old female with intermittent vertical strabismus of 20PD and -2 limitation on depression, worse in abduction. MRI imaging showed a hypoplastic IR. Following surgery,...

Brolucizumab in age-related macular degeneration, HAWK Study

The aim of the study was to collect additional data on efficacy and safety of brolucizumab 6mg intended for commercialization in age-related macular degeneration (AMD) (with an increase in pH and decrease in polysorbate concentration). The HAWK Study was a...

Ophthalmic presentations and outcomes in Erdheim-Chester disease

This is a comprehensive article describing clinical manifestations and pathogenesis of Erdheim-Chester disease (ECD) followed by a literature review of the available treatments. The authors look to compare historical treatment (HT) with vemurafenib, a BRAF inhibitor. ECD is a non-Langerhans...

Acute comitant esotropia as the presenting sign of diffuse intrinsic pontine glioma

The authors present four children with acute comitant esotropia (AACE) associated with diffuse intrinsic pontine glioma. All were treated with radiation therapy and all subsequently died due to the tumour. Children were aged 5, 5, 4.5 and 11 years. General...

Aquaporin-4 antibody testing in isolate optic neuritis

The authors present a retrospective case review of first presentation isolated cases of optic neuritis tested for aquaporin-4 antibody across two centres over a nine-year period. Exclusion criteria included known diagnosis or other manifestations of neuromyelitis optica spectrum disorder. Two...

Natural history of optic nerve head drusen in a paediatric population

A retrospective case notes review is presented focusing on children diagnosed with optic nerve head drusen over an eight-year period. Inclusion criteria included cases coded for optic nerve head drusen and / or pseudopapilledema. The aim of the study was...

Ophthalmic findings following noticeable external injury following forceps delivery

This study prospectively recruited consecutive women following a forceps vaginal delivery of a single foetus in cephalic position over a two-year period. Individual patient consent was waived by the approving body. The neonates received a paediatrician assessment soon after birth....

Features and outcomes of pulled-in-two syndrome

Pulled-in-two (PIT) syndrome is a sudden rupture of the extraocular muscle during strabismus surgery, typically with minimal tension intraoperatively without excessive force. This is a rare occurrence and this study reports cases from a single centre over a seven-year period....