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Effect of long-term scleral contact lenses on corneal topography, tear film and impression cytology in keratoconus

This study of 16 keratoconus patients aimed to investigate the impact of long-term scleral contact lens (ScCL) wear on corneal curvature, corneal thickness, tear film function and ocular surface in patients with keratoconus. Corneal topography, tear osmolarity test, Schirmer 1...

OCT biomarkers in asymmetric anti-VEGF response in bilateral diabetic macular oedema

This study aimed to identify optical coherence tomography (OCT) biomarkers for predicting response to anti-VEGF treatment in diabetic macular oedema (DMO). Bilateral DMO patients with asymmetric response to a loading dose of anti-VEGF (ranibizumab / aflibercept) treatment were retrospectively studied....

Questionable ERG use for Vigabatrin screening

The authors aimed to identify the usefulness of electroretinograms (ERGs) as screening for retinal toxicity in patients taking Vigabatrin in a single centre study. This was a retrospective review of full field ERGs and included 170 ERGs of 138 patients...

Screening outcomes for Syrian refugee children

This study compared two commonly used photoscreeners in a Syrian refugee camp in Jordan to better understand what types of technology would function best in a low-resource setting. The children in this study were assessed with the PEEK acuity application...

Transcriptomic and regulatory gene associations in open angle glaucoma

The authors report a study utilising a publicly available whole exome sequencing dataset of 28 patients with primary open angle glaucoma (POAG) and seven healthy control patients, and a transcriptomic dataset from the trabecular meshwork of four POAG patients and...

Ethnic disparities in diagnostic sequencing yield

The authors present a systematic review and meta-analysis of the diagnostic yield of next generation sequencing (NGS) for inherited retinal diseases and compare yield from studies performed primarily on patients of European descent from those primarily of East Asian descent....

Birmingham Optical Achieves UKAS ISO 9001 Certification

Birmingham Optical, a leading UK provider of optical equipment and services, has been awarded the prestigious UKAS ISO 9001 certification, a globally recognised standard for quality management systems (QMS). This milestone reflects the company’s dedication to excellence, consistency, and customer...

High-stakes scenarios in retinal vein occlusion: A survey of medico-legal implications

Central retinal vein occlusion (CRVO) is the second most common retinal vascular disease after diabetic retinopathy, and its clinical complexity often intersects with medico-legal scrutiny [1]. Missteps in timely diagnosis, inadequate follow-up or poor documentation can lead to patient harm...

A paediatric case of central retinal artery occlusion following antibiotics and decompression surgery for orbital cellulitis

Orbital cellulitis is an ophthalmic emergency that warrants urgent management in the hospital setting [1]. This occurs more frequently in the paediatric population where it is often secondary to sinus infections. Delay in treatment could result in severe complications including...

Nanosecond laser cataract surgery

The authors review the evidence for nanosecond laser cataract surgery: is this the future? Cataract is a leading cause of visual impairment worldwide, and cataract surgery is one of the most successful and cost-effective healthcare interventions, with a great impact...

The International Council of Ophthalmology: what is it and is it useful for UK ophthalmologists?

ICO Director for Examinations and Assessments, Simon Keightley, explains the history and role of the organisation today, as well as outlining recent changes to the ICO examinations. The International Council of Ophthalmology (ICO) is the only international medical specialty organisation...

What's trending Oct/Nov 2023

A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #Hello A big hello to those reading. It’s my absolute pleasure to take on the mantel of section editor of the...