Search

Corneal stroma modelling under hypoxic conditions

The cornea is exposed to hypoxia under several conditions including sleep, inflammation and wound healing. Being an avascular tissue to maintain transparency, how the cornea homeostatic controls oxygen tension is important. To address this process two models were utilised; a...

Medical malpractice in uveitis: a review of clinical entities and outcomes

This paper presents a retrospective review of malpractice verdicts, rulings and settlements in the United States. Twenty-five cases of uveitis-related litigation spanning 1971-2014 were identified from the database representing 2.3% of all cases. Forty-eight percent of the cases were infectious....

MISS vs. conventional surgery

This was a prospective randomised parallel arm design study for 40 patients. Group 1 consisted of conventional strabismus surgery using the limbal approach and group 2 consisted of minimally invasive strabismus surgery (MISS). Mean age was 21.1±2.73 years for MISS...

Uveitis in the elderly

This study from Turkey evaluated the causes and clinical characteristics of uveitis in elderly patients. Data from 90 eyes of 68 patients aged 60 years and older were reviewed. Anterior uveitis was present in 75% (33% of these had keratouveitis),...

Nanoparticle administration of latanoprost

Glaucoma is a progressive optic neuropathy characterised by increased ocular pressure and loss of retinal ganglion cells. Conventional drug therapy with eye drops to reduce intraocular pressure (IOP) has variable bioavailability and can lead to ocular surface disease. In this...

Use of amniotic membrane in second stage Hughes tarsocunjunctival reconstruction

This is a retrospective, non-comparative interventional case series of 30 patients who underwent amniotic membrane transplantation to lower lid margin as part of Hughes lid reconstruction to prevent a hyperaemic, hypertrophic conjunctival margin with excessive discharge. Patients undergoing more than...

IgG4-related disease or Graves orbitopathy

This is retrospective review of patients who had been diagnosed with both IgG4-related ophthalmic disease (IgG4-ROD) and Graves orbitopathy over a four year period. Eight patients were identified. The diagnosis of IgG4-ROD was based on 10 or more IgG4+ plasma...

Thyroid eye disease and obstructive sleep apnoea

This is a retrospective study looking for an association between compressive optic neuropathy in thyroid eye disease (TED-CON) and obstructive sleep apnoea (OSA). One hundred and nine patients with thyroid eye disease were asked to complete a validated questionnaire designed...

Intraocular pressure reduction after cataract surgery

Several studies have shown the efficacy of cataract surgery in lowering intraocular pressure (IOP), especially in angle closure glaucoma compared to open angle. A total of 156 eyes of 109 patients (without glaucoma or with medically controlled glaucoma) were included....

A novel presentation of optic disc oedema with syphilis

Optic disc oedema (ODE) due to syphilis without visual compromise has been primarily attributed to papilloedema from raised intracranial pressure or optic perineuritis from optic nerve sheath inflammation. These terms were proposed before magnetic resonance imaging (MRI) was largely available....

Orbital cellulitis outcomes for children

This paper discusses the clinical profile and multidisciplinary team (MDT) management outcomes in children treated for paediatric orbital cellulitis. This was a prospective study of 40 children with a mean age of 7.5 years (4-12). Unilateral orbital cellulitis cases had...

Clinical features of ocular syphilis

The study looked at 24 patients (20 males, four females) with serological evidence of syphilitic infection who presented to a tertiary ophthalmic centre. Ocular involvement was the first manifestation of syphilitic disease in 96% and Human Immunodeficiency Virus (HIV) seropositivity...