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848 results found

Intra-arterial carboplatin therapy not associated with hearing loss

The aim of this study was to determine if administration of intra-arterial carboplatin (IAC) affected the hearing of children being treated for retinoblastoma. This was a prospective study in which 22 of 40 consented children completed therapy. Hearing was tested...

Effect of intra-arterial chemotherapy drug regimens on globe salvage outcomes of retinoblastoma patients

This is a retrospective study from Shandong University, China, between May 2016 to November 2019, to compare the effect of 3-drug regimen (melphalan (MP) , topotecan (TP) and Carboplatin (CP)) of 95 patients (97 eyes) with two-drug regimen (MP and...

Nonarteritic anterior ischaemic optic neuropathy

This review article describes nonarteritic anterior ischaemic optic neuropathy (NAION). This condition is one of the common causes of visual loss in adults. The article uses a good range of references and is divided under the headings of; demographics, clinical...

Choroidal and macular thickness in nonarteritic anterior ischaemic optic neuropathy

This study evaluates the choroidal and macular thickness in patients with chronic nonarteritic anterior ischaemic optic neuropathy (NA-AION). Two groups of subjects were compared, group one included 20 eyes with chronic NA-AION and group two, 31 healthy control eyes. The...

Retina Subspecialty Day highlights from the RCOphth 2026 Annual Congress

Implementation of biosimilars in NHS retinal services A NHS England (NHSE) perspective Luke Nicholson (Moorfields Eye Hospital) explained that the NHSE perspective overall is structured on best value medicine for the patient and system, accounting for a finite budget and...

Blurred vision post liver transplant: to blame the house cat or not?

This article outlines a case of atypical ocular toxoplasmosis associated with immunosuppression. There were two potential sources of infection in this patient and we describe how we concluded which was the most likely. Case report A 33-year-old female was referred...

My Top Five: Key insights from recent research into uveitis in adults

Uveitis, characterised by inflammation of the uvea – the eye’s middle layer comprising the iris, ciliary body, and choroid – remains a leading cause of visual impairment worldwide [1]. It primarily affects adults aged 20–50 years. Untreated uveitis may cause...

Maximising the ocular surface prior to cataract surgery: The old and the new modalities of treatment

Cataract surgery is among the most commonly performed surgical procedures worldwide. Over time, it has evolved from a lens-extraction procedure into a refractive intervention that demands meticulous perioperative planning and precision to achieve optimal outcomes. Optimisation of the ocular surface...

Intraocular surgery and dry eye: Understanding the link, minimising the risk and preparing for the future

Dry eye disease (DED) and ocular surface disease (OSD) are increasingly recognised as central factors in contemporary intraocular surgery. As cataract, glaucoma and vitreoretinal procedures advance toward greater refractive precision, patient expectations have risen and tolerance for postoperative visual fluctuation...

Acute management of retrobulbar haemorrhage

The authors discuss the importance of rapid diagnosis and correct management of acute RBH presentation to avoid the risk of permanent blindness. Retrobulbar haemorrhage (RBH) is an ocular emergency that occurs due to arterial bleeding in the orbital cavity behind...

Outcomes of plaque radiotherapy for retinoblastoma

The study authors evaluate their experience of plaque radiotherapy for retinoblastoma (RB) in 41 eyes of 41 patients that failed intra-arterial chemotherapy (IAC). This was a retrospective review including 21 females and 20 males. Median age was 18 months and...

Comparison of thrombolysis and conservative management in acute retinal ischaemia

The authors present a retrospective cohort study of individuals presenting with acute, painless, monocular vision loss and diagnosed with acute retinal ischaemia. Reasons for exclusion were iatrogenic aetiology, transient vision loss, missing initial visual acuity data, more than 16 hours...