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Renewed momentum in ocular gene and cell therapy, broadening application to chronic disease

Gene and cell therapies offer the prospect of ground-breaking new avenues for the treatment of diseases, reflected in a renewed explosion of interest and investment in retinal gene therapy. Rod McNeil reports recent clinical trial readouts across a diverse range...

Personalising the management of dry eye disease: TFOS DEWS III updates evidence-based recommendations

Dry eye disease (DED) is a heterogenous condition that arises from various aetiologic factors and leads to tear film instability, ocular surface damage and neurosensory changes. Symptoms of DED include ocular dryness, burning, itching, pain and visual impairment. An evidence-based...

East Bound and Down: Patrick Staropoli

One of my heroes growing up in the 70s was the iconic Formula 1 racing driver, James Hunt. At the time, if you had asked me and my primary school friends what we would most like to do for a...

East Bound and Down: Patrick Staropoli

One of my heroes growing up in the 70s was the iconic Formula 1 racing driver, James Hunt. At the time, if you had asked me and my primary school friends what we would most like to do for a...

Through the bubble: A patient’s perspective on macula hole surgery pre- and postoperatively

The evolution of ophthalmic surgical practice over the past seven decades has been extraordinary. Within this period, the first vitrectomy was performed, establishing a foundation for what is now an operation performed thousands of times per year in the UK...

Ophthalmology in ancient india, Sushruta’s time and the modern era

While reading an article related to the history of Indian ophthalmology, I came across this description of a surgical procedure: “The doctor warmed the patient’s eye with the breath of his mouth. He rubbed the closed eye of the patient...

Volunteer abroad: the Khmer Sight Foundation

A team of volunteers describe their experiences of working with the Khmer Sight Foundation in Cambodia. Cambodia has a population of 15 million people, of whom an estimated 300,000 are blind. This figure is increasing by 10,000 each year. Three-quarters...

A three-way partnership between Nigeria, Tanzania and Northern Ireland

VISION 2020 LINKS between Western Health and Social Care Trust (WHSCT), Altnagelvin Area Hospital, Northern Ireland with first ECWA Eye Hospital, Kano, Nigeria and now also with Mbeya Referral Hospital (MRH), Tanzania, have been beneficial to all three partners. From...

Primary eye health care in low- and middle-income countries

The need for eyecare services in low- and middle-income countries Recent global estimates (2020) suggest that there is more than a three-fold difference in the prevalence of all categories of visual loss (presenting visual acuity <6/12 in the better eye)...