Search

The effects of ab-interno XEN gel implantation on postural IOP elevations

The study involved 18 patients with XEN gel implants, 30 patients who had trabeculectomy, and 30 medically managed glaucoma patients. All patients in XEN gel implant and trabeculectomy groups had at least 11 months of follow-up following successful surgery resulting...

Effect of long-term scleral contact lenses on corneal topography, tear film and impression cytology in keratoconus

This study of 16 keratoconus patients aimed to investigate the impact of long-term scleral contact lens (ScCL) wear on corneal curvature, corneal thickness, tear film function and ocular surface in patients with keratoconus. Corneal topography, tear osmolarity test, Schirmer 1...

OCT biomarkers in asymmetric anti-VEGF response in bilateral diabetic macular oedema

This study aimed to identify optical coherence tomography (OCT) biomarkers for predicting response to anti-VEGF treatment in diabetic macular oedema (DMO). Bilateral DMO patients with asymmetric response to a loading dose of anti-VEGF (ranibizumab / aflibercept) treatment were retrospectively studied....

Questionable ERG use for Vigabatrin screening

The authors aimed to identify the usefulness of electroretinograms (ERGs) as screening for retinal toxicity in patients taking Vigabatrin in a single centre study. This was a retrospective review of full field ERGs and included 170 ERGs of 138 patients...

Screening outcomes for Syrian refugee children

This study compared two commonly used photoscreeners in a Syrian refugee camp in Jordan to better understand what types of technology would function best in a low-resource setting. The children in this study were assessed with the PEEK acuity application...

Transcriptomic and regulatory gene associations in open angle glaucoma

The authors report a study utilising a publicly available whole exome sequencing dataset of 28 patients with primary open angle glaucoma (POAG) and seven healthy control patients, and a transcriptomic dataset from the trabecular meshwork of four POAG patients and...

Ethnic disparities in diagnostic sequencing yield

The authors present a systematic review and meta-analysis of the diagnostic yield of next generation sequencing (NGS) for inherited retinal diseases and compare yield from studies performed primarily on patients of European descent from those primarily of East Asian descent....