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Lockdown and eye health – a case of accommodative spasm

A 25-year-old male presented to the eye casualty with a one-day history of sudden onset worsening vision. More specifically, he noted his vision was more blurred than usual and this was more exaggerated for near-work than for distance-work. He was...

Retinal Vein Occlusions: Evidence-based Management

This reference book is designed to enable an ophthalmologist to make diagnostic and treatment decisions on the basis of the available scientific evidence. This is a very comprehensive book covering all aspects of central retinal vein occlusions including basics, clinical...

Ophthalmology Lecture Notes (Twelfth Edition)

During medical school, our seniors often told us that the easiest way to remember something is to understand it. And rightly so, when I came across the Ophthalmology Lecture Notes textbook as a student I realised that the key to...

Self refracting – child’s play?

Uncorrected refractive error was the leading cause of vision impairment in the world in 2010. Although refractive error may be safely and effectively corrected with spectacles, lack of well-trained refractionists in settings of limited resources may be a major barrier....

Vision loss during Eylea treatment for AMD

This report investigated patients who lost more than two lines of vision despite periodic injections of aflibercept and explored the factors associated with vision loss. One hundred and ninety-six eyes were included in this study over a two year period....

Femto-DMEK – a solution for high re-bubbling rates?

This retrospective study examined results of patients that underwent femtosecond laser enabled descemet membrane endothelial keratoplasty (DMEK) (FE-DMEK) and manual DMEK (M-DMEK) for Fuch’s endothelial dystrophy. In FE-DMEK femtosecond laser was used to create 8.25mm descemetorhexis, whereas during M-DMEK- descemetorhexis...

Retrograde maculopathy in glaucoma

Macular optical coherence tomography (OCT) analysis can be used for quantitative measures of optic nerve atrophy at a location far away from the optic nerve head. This has recently led to the discovery of microcystic macular oedema (MME), in the...

Glaucoma diagnosis with spectral-domain OCT of GCL and IPL

This is a prospective, cross-sectional, observational study by the New York Eye and Ear Infirmary, which recruited normal subjects and glaucoma patients with a range of visual field loss representing various degrees of glaucomatous optic neuropathy. A total of 69...

Stromal cell alignment in damaged cornea

Stromal keratocytes are responsible for wound healing in the cornea following damage. Keratocytes at the site of injury become activated and differentiate to myofibroblasts which secrete extracellular matrix (ECM) to close the wound, a response mediated by transforming growth factor...

Finasteride and central serous chorioretinopathy

The pathophysiology of central serous chorioretinopathy (CSC) is complex and has not been fully elucidated. Suggested theories include hyperpermeability and increased hydrostatic pressure in the choroidal vasculature, which creates RPE detachments overwhelming the RPE barrier function, leading to accumulation of...

Wrong intraocular lens events – what lessons have we learned?

Data from wrong IOL patient safety incidents (PSIs) submitted to the National Reporting and Learning System (2010–2014) were reviewed and scrutinised by thematic analysis and compared with the historical data collected for groups in 2003-2010, prior to the mandatory checklist...

Late stromal rejection in DALK

This case series reported on late stromal rejections in eyes after uncomplicated deep anterior lamellar keratoplasties (DALKs). Four eyes of three patients experienced episodes of isolated stromal rejection 33 to 46 months after surgically uncomplicated DALKs and a minimum of...