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Do steroids prevent progression to proliferative diabetic retinopathy (PDR)?
1 February 2017
| Usha Chakravarthy (Prof)
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EYE - Vitreo-Retinal
There is continuing debate on the merits of pan-retinal photocoagulation (PRP) for severe pre-proliferative and proliferative DR versus the newer therapies that inhibit vascular endothelial growth factor (VEGF). This has been hotly debated [1] following the publication of findings from...
Zeiss Forum
1 December 2016
| David Haider
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EYE - Imaging
The tech column this issue reports on the features and experience of using the Zeiss Forum software. I have overseen the installation, troubleshooting, training and use of the software over the last two years. As both a consultant specialising in...
MR- vs. LR+ for divergence insufficiency
A retrospective study was conducted to compare the efficacy of medial rectus recession and lateral rectus resection as surgical interventions for divergence insufficiency in 18 patients. These were cases of non-neurological cause. Two patients in each group required postoperative adjustment....
Infantile exotropia and developmental delay
This is a retrospective review of infants requiring surgery for infantile exotropia before the age of one year to report the surgical outcomes and frequency of associated developmental problems. The study reviewed 26 patients first assessed at two to 10...
Outcomes of strabismus surgery for TED
This study investigated the surgical outcome according to the initial postoperative angle of deviation after strabismus surgery in patients with hypotropia and esotropia who had thyroid eye disease (TED). The study included 78 patients with mean age of 53.4 ±9.5...Immunoglobulin G4-related ophthalmic disease – what is it? (Part 1)
3 February 2023
| Li Yen Goh
|
EYE - General
Part 1: Epidemiology, classification, radiology, histopathology and associations (see Part 2 here) In this two-part series, Li Yen Goh reviews IgG4 disease and reminds us of diagnostic challenges faced. Introduction Immunoglobulin G4 (IgG4) disease is a recently recognised idiopathic systemic...
Exeter clinic manager wins VCHP Volunteer Award
Exeter VCHP clinic manager, Zoe Haigh, has been recognised for her outstanding contribution to the charity during the past six years.3rd Annual Retinal Imaging Biomarkers & Endpoints Summit
27 May 2025
-29 May 2025
Accelerate Your Ophthalmic Development with Deep Learning Systems & Sophisticated AI Imaging TechnologiesWith state-of-the-art AI-assisted technology making retinal imaging 100 times faster, the rapid advancement of technology in ophthalmology, coupled with the strong unmet need for more drugs for retinal...
A possible biomarker for diabetic retinopathy
1 August 2017
| Graham Wallace
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EYE - Vitreo-Retinal
Diabetic retinopathy (DR) is the most common form of diabetic eye disease, characterised by exudates, microaneurysms and haemorrhage. Early diagnosis is crucial for preventing visual loss. The risk of developing diabetic retinopathy is known to increase with age as well...
RPE use similar pathway to regulatory T cells to inhibit immune response
1 December 2014
| Graham Wallace
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EYE - Vitreo-Retinal
Retinal pigment epithelial (RPE) cells form an important part of the blood-retinal barrier that protects the neuronal cells responsible for sight. RPE cells are involved in innate and adaptive immune responses via expression of surface molecules and release of cytokines....
The effect of everolimus on retinal pigment epithelium and proliferative vitreo-retinopathy
1 August 2018
| Kurt Spiteri Cornish
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EYE - Vitreo-Retinal
The principal cells involved in proliferative vitreo-retinopathy (PVR) are retinal pigment epithelial cells (RPE). Everolimus is a drug used in renal cell carcinoma which targets and inhibits a key regulatory protein in cancer (mTOR). In this study, the authors investigated...
How the thinking machine is transforming the retinal landscape
1 May 2025
| Zhihang Cheng
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EYE - Vitreo-Retinal
Regulatory approval of the first two therapeutic substances for the management of geographic atrophy (GA) secondary to age-related macular degeneration has been a major breakthrough. The authors explored the issue surrounding the lack of agreed therapeutic standards and diagnostic tools...
