You searched for "regulation"

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Importing iron to the retina

In the retina, iron is particularly critical for the visual phototransduction cascade. In the retinal pigment epithelium (RPE), RPE65 activity leads to 11-cis-retinaldehyde, the photosensitive component of rhodopsin production and iron containing enzymes are necessary for disc replacement in photoreceptor...

Glasgow eye department continues to disrupt ocular simulation training through novel DRV system - the first of many?

Ongoing technological developments are enabling continuous progress to be made across all aspects of medical simulation training. This is particularly true within the field of ophthalmology, where surgical training advancements have enabled the role of simulation to expand dramatically over...

Glasgow eye department continues to disrupt ocular simulation training through novel DRV system - the first of many?

Ongoing technological developments are enabling continuous progress to be made across all aspects of medical simulation training. This is particularly true within the field of ophthalmology, where surgical training advancements have enabled the role of simulation to expand dramatically over...

Seeing with fresh eyes: Snails as a system for studying sight restoration

Stowers scientists have established the apple snail as a new research organism for investigating eye regeneration, which may hold the key for restoring vision due to damage and disease. Snails are slimy, simple creatures yet one species, the apple snail,...

Understanding optic nerve head pericytes and glaucoma

The authors provide a comprehensive review of the current understanding of pericytes in the optic nerve head (ONH). Key points include: (1) Pericytes are contractile mural cells that play crucial roles in regulating blood flow, maintaining the blood-brain / blood-retinal...

What’s new in glaucoma? Clinical trials drive practice changes, surgical advancements gather pace

Rod McNeil reviews the latest developments in the treatment of glaucoma in the UK. Primary open-angle glaucoma (POAG), which accounts for over two-thirds of all glaucoma cases, has an estimated UK prevalence in 2017 of approximately 2% of people over...

Selective laser trabeculoplasty after medical treatment

Selective laser trabeculoplasty (SLT) is a well-established treatment for open-angle glaucoma (OAG) and ocular hypertension (OHT). This post-hoc secondary analysis of the LiGHT trial extension examined SLT as a secondary intervention after 3 years of protocolised medical therapy in patients...

Automated Bruckner device accuracy

The authors developed a Bruckner device, examined volunteers and determined the relation between the luminance of the red fundus reflex and eye rotation. Eye rotation was varied continuously both horizontally (-7 to 8 degrees) and vertically (five degree total range)...

The vitreoretinal priesthood

When I first started doing cataract lists, the consultant at the time, a Mr Brown from Carmarthen, used to say that phacoemulsification was more akin to flying a jet fighter for short dangerous bombing runs than a boring long haul...

ROPScore for detection of any and severe ROP

ROPScore is a free tool consisting of a logistic regression equation to calculate the risk per child and calculated one time per infant at six weeks of life. It helps to predict severe retinopathy of prematurity (ROP). This study aimed...

Implementing technology to improve global eye health

Technological innovation is providing new solutions to transform global eye health [1–5]. In particular, research towards the development of artificial intelligence (AI) tools in ophthalmology has gained pace in recent years. However, there has been little research relating to its...

Fungi in chronic anterior blepharitis

In this prospective, non-randomised cross-sectional study the authors demonstrate the presence of fungi in patients with chronic anterior blepharitis of at least two years duration. Eyelash samples were obtained by epilation with sterile forceps and evaluated with PAS staining, fungal...