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Ophthalmology Secrets, Fifth Edition

Janice Gault presents the fifth edition of the critically acclaimed Ophthalmology Secrets. If you are someone like me, who is sceptical and needs persuaded to add another textbook to their collection, let me be the first to convince you the...

Is patient masking leading to an increase in post-op infection after eyelid surgery?

Due to the COVID-19 pandemic, the use of facemasks or face coverings in the clinical setting has become necessary. It is important to recognise that facemasks can be a source of infection after eye surgery and consider ways to minimise...

A guide to the Multi-Speciality Recruitment Assessment (MSRA) exam

The MSRA exam is a mandatory part of the application for ophthalmology specialist training in the UK. It is a computer-based exam which is designed to assess junior doctors with foundation level competence. It is used for entry to postgraduate...

C-spp corneal consequences

This is a retrospective review of microbiological records of 22 patients, who had presented at the LV Prasad Eye Institute, India, between June 2009 and December 2012. The corneal scrapings were performed in all patients and had yielded significant growth...

Carbonic anhydrase II autoantibody specificity in retinopathy

Autoimmune retinopathy (AR) can be divided into three different categories, paraneoplastic retinopathy, including recoverin-associated retinopathy and melanoma-associated retinopathy, non-paraneoplastic autoimmune retinopathy, combined paraneoplastic optic neuropathy and retinopathy (CAR). These conditions are characterised by circulating anti-retinal autoantibodies, possibly due to a...

Mast cells in Graves’ ophthalmopathy

Graves’ ophthalmopathy (GO) is a potentially sight-threatening ocular disease, occurring in patients with hyperthyroidism due to Graves’ disease. Also known as thyroid-associated ophthalmopathy, GO is characterised by orbital infiltration by immune cells including macrophages, T cells and plasma cells, which...

ICG TTT for retinoblastoma

Transpupillary thermotherapy (TTT) is a specific form of ocular TT using infrared radiation (diode laser). Indocyanine green (ICG) is also used to achieve the optimal phototherapy effect in eyes with minimal pigment. Twenty-one patients with 42 retinoblastomas in 30 eyes...

Comparison of SS-OCT and SD-OCT in polypoidal choroidal vasculopathy

Swept source OCT (SS-OCT) is known to have a longer wavelength than spectral domain OCT (SD-OCT), allowing deeper penetration into retinal and choroidal layers. The aim of this study was to investigate whether SS-OCT is superior to SD-OCT in imaging...

Sex differences in the relationship between obesity and choroidal nevus in US adults

The National Health and Nutrition Examination Survey (NHANES); a population-based survey conducted annually in the US by the Centers for Disease Control and Prevention, was used to identify populations at higher risk for choroidal naevus. Over a period of four...

Transfected RPE cells inhibit AMD in rats

Age-related macular degeneration (AMD) is a leading cause of blindness in the elderly. Wet AMD is characterised by choroidal neovascularisation, new vessels into the retina, leading to leakage and tissue damage. Many proangiogenic factors particularly vascular endothelial growth factor (VEGF)...

A randomised, controlled trial of oral propranolol in infantile haemangioma

Since its use was first reported in the New England Journal in 2008, propranolol has become the preferred treatment for infantile haemangiomas. However, there is no consensus as to the optimum dose or duration of treatment and there is a...

Do topical steroids improve visual outcome in the treatment of bacterial keratitis?

The use of topical corticosteroids as an adjunctive treatment to antibiotics in the management of bacterial keratitis remains a controversial issue. The results of the Steroids for Corneal Ulcers Trial (SCUT) – a randomised, double-masked, placebo-controlled trial that recruited patients...