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Experimental Eye Research cover image.

ANGPTL-4 inhibition reduces inflammation in diabetic retinopathy

1 June 2018 | | EYE - Vitreo-Retinal
Diabetic retinopathy (DR) is the most common cause of blindness in working-age humans, and numbers are rising due to increased cases of type 2 diabetes (T2D). T2D is associated with increased obesity and dyslipidaemia, which is a major risk factor...
Neuro-ophthalmology front cover image.

Surgical success rates in abducens palsy management

1 April 2015 | | EYE - Neuro-ophthalmology | Adjustable suture, cranial nerve palsy, hummelsheim, paralytic strabismus, sixth nerve palsy
The aim of the study was to identify factors associated with surgical outcomes in isolated abducens palsy. To achieve this goal the authors reviewed the records of adult patients with abducens palsy who underwent strabismus procedures during a fourteen year...
Experimental Eye Research cover image.

MicroRNA inhibits corneal neovascularisation

1 August 2018 | | EYE - Cornea, EYE - General | Biomechanical stress, Corneal epithelium, MicroRNA-204, Neovascularization, VEGF, VEGFR2
MicroRNAs (miR) are small non-coding RNA that target mRNA for destruction. MiR target about 30% of the protein coding genes and fine tune their expression. MiR have been shown to be involved in several cellular processes including cell cycle, tissue...
Ophthalmic Epidemiology cover picture

Association between diabetes mellitus and dry eye disease

1 April 2020 | | EYE - Vitreo-Retinal
Diabetes mellitus (DM) is currently one of the most prevalent chronic diseases in the United States. It is estimated that 12.3% of Americans suffer from DM. In this study the authors compare between dry eye and diabetes mellitus among a...
Strabismus journal cover image.

Recovery outcomes for ocular cranial nerve palsies

30 May 2025 | | EYE - Paediatrics, EYE - Strabismus
The aim of this study was to report the different causes and recovery patterns for patients with acquired and isolated ocular cranial nerve palsies in a prospective observation study of 80 consecutive patients in a single centre. There were 40...
Journal of Pediatric Ophthalmology & Strabismus cover image.

Changes in retinal and choroidal microcirculation after strabismus surgery

4 August 2025 | | EYE - Strabismus
The aim was to evaluate retinal and choroidal microcirculation using optical coherence tomography angiography after strabismus surgery. This was a cross-sectional observation study of 44 eyes of 44 patients. Patients were split into three groups: (1) one-muscle horizontal surgery (n=9);...
Progress in Retinal and Eye Research journal front cover image.

Understanding optic nerve head pericytes and glaucoma

4 December 2025 | | EYE - Glaucoma
The authors provide a comprehensive review of the current understanding of pericytes in the optic nerve head (ONH). Key points include: (1) Pericytes are contractile mural cells that play crucial roles in regulating blood flow, maintaining the blood-brain / blood-retinal...

Radiation retinopathy

5 June 2020 | | EYE - Vitreo-Retinal, EYE - General
The authors review the current treatment options for this condition. Radiation retinopathy (RR) occurs as a complication after exposure to any type of radiation (external beam, plaque brachytherapy and stereotactic radiosurgery) in the orbital or adnexal region. These include nasopharyngeal...

Safety and efficacy of a nurse-led intravitreal injection service using an Precivia® injection assist device

1 December 2021 | | EYE - Vitreo-Retinal, EYE - General
Nurse-led intravitreal injections have become of great importance for busy eye units. In this article, the authors present safety data from five years of a nurse-led service with the use of the Precivia® intravitreal injection assist device. Intravitreal injections of...

Diabetes and diabetic retinopathy: Changes in understanding of the disease over the last 25 years and how the UK is helping low-income countries tackle the challenges

1 June 2018 | | EYE - Vitreo-Retinal, EYE - General
Diabetes – a historical perspective Diabetes mellitus (DM) is a chronic disease caused by inherited and / or acquired deficiency in production of insulin by the pancreas, or by the ineffectiveness of the insulin produced. Such a deficiency results in...

Eye research: where next?

1 December 2017
Eye research in the UK is underfunded relative to other areas of medical research and general awareness of sight loss and its prevention remains poor, messages that were reinforced in presentations and discussions during a recent research summit meeting in...

Coming to terms with AI

1 August 2019 | | EYE - Imaging, EYE - Vitreo-Retinal, EYE - Glaucoma, EYE - General
A machine might be called intelligent if its response to questions could convince a person that it was human, a test proposed by Alan Turing in 1950 [1]. The author considers potential applications of artificial intelligence (AI) using machine learning...