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The history, evolution and future of optical coherence tomography

OCT has made it possible to capture a detailed 3D image of the retina, revolutionising ophthalmic diagnostics and optometric practice. Professor Fujimoto, inventor of OCT, visits us from MIT to speak on the transformative impact of OCT and its future role in AI diagnostics, vision and wider healthcare.

Vitreoretinal Disease: Diagnosis, Management and Clinical Pearls (second edition)

A comprehensive, well-illustrated and highly informative resource providing excellent descriptions of vitreoretinal diseases, their presentation, diagnosis and management. The 40 chapters are grouped into four sections, namely: the Anatomy and Physiology of the vitreous, retina, choroid and retinal pigment epithelium;...

Pathophysiology of diabetic macular oedema: why combination therapy may be better

The prevalence of diabetes has continued to increase over the years. It is currently estimated that there are 382 million with diabetes worldwide in 2013, and that this figure is expected to rise to 592 million by 2035 [1]. In...

Association between neurodegeneration and macular perfusion in the progression of diabetic retinopathy

In this prospective three-year longitudinal study, the authors aimed to explore the relation between retinal neurodegenerative changes and vessel closure (VC) in individuals with non-proliferative diabetic retinopathy (NPDR). The participants included 74 individuals with type 2 diabetes, NPDR, and Early...

Normal reference values for the RETeval device

The purpose of this study was to provide normative data of full-field electroretinography (ERG) responses in the paediatric population using the RETeval device in healthy children with normal retinas. This was a prospective study of 38 eyes of 20 patients...

Moorfields: Vitreoretinal emergencies: A practical guide for health care professionals

Vitreoretinal emergencies: A practical guide for health care professionals

CRATER 2025

The Conference on Recent Advances in Translational Eye Research 2025

A log in the eye

"My friend wanted to show how far he could throw that log. So, he helicoptered it over his head, faster and faster and when he let go, it hit my eye at full speed,” a young lady of 19 years...

Ocular toxicity secondary to deferoxamine

Patients with myelodysplastic syndromes can develop transfusion-related iron overload as they become dependent on recurrent blood transfusions [1]. Iron chelation therapy is indicated for the treatment of iron overload and one established example of this is deferoxamine. However, deferoxamine ocular...

What’s next in retinal imaging? Faster, deeper and full-on

Fast-evolving technological leaps are opening the way toward clinically useful ocular coherence angiography, generating 3-dimensional microvasculature maps without intravenous dye injection, as well as whole-eye imaging, handheld patient-operated optical coherence tomography (OCT) devices and, for challenging vitreoretinal procedures, integrated intraoperative...

OCTA FAZ measurements in vein occlusion

Previous studies have confirmed that foveal avascular zone (FAZ) enlargement is correlated with visual acuity impairment in patients with retinal vein occlusion (RVO). This current study aimed to evaluate the OCT angiography parameters: the area of FAZ, foveal and parafoveal...

Brn3b neuroprotective effect in rat glaucoma model

An adeno-associated virus-directed overexpression of the Brn3b protein in hypothesised to confer neuroprotective effects in this paper. This is ultimately tested in a well-accepted rat glaucoma model (Morrison’s model: saline injection into episcleral veins of rat eyes with a force...