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My Top Five: Promising gene therapies for ocular conditions

Gene therapy, a pivotal advancement in modern medicine, particularly shines in ophthalmology. By targeting defective genes with engineered vectors, this approach promises significant strides in treating inherited retinal diseases. This article reviews the top five gene therapies in late-stage trials,...

Oculoplastic Surgery (Third Edition)

This is a single author textbook in its third edition that reflects the author’s extensive experience and also their detailed, methodical and organised approach to oculoplastic, orbital and lacrimal surgery. It is a widely known and popular textbook, not only...

Essentials of OCT in Ocular Disease

Sir Isaac Newton was the first to establish the technique of low coherence white light interferometry. Following on from this, the principle of laser interferometry as an imaging modality for retina was applied by David Huang and his associates in...

RaScaL Study

The RaScaL study was a six month, single-centre, controlled, prospective phase I/II study in which subjects with diabetic macular oedema (DME) and associated peripheral nonperfusion on ultrawide-field fluorescein angiography (UWFA) were randomised to: (1) study arm: ranibizumab (0.5 mg) injection...

Retinal Vein Occlusions: Evidence-based Management

This reference book is designed to enable an ophthalmologist to make diagnostic and treatment decisions on the basis of the available scientific evidence. This is a very comprehensive book covering all aspects of central retinal vein occlusions including basics, clinical...

Transient thickening of the macular retinal nerve fibre layer in acute optic neuritis

Acute optic neuritis (ON) causes axonal degeneration, which can be quantified from the blood by neurofilament protein (Nf) levels. Within about three months, atrophy of the retinal nerve fibre layer (RNFL) follows. However, it remains challenging to explain why there...

Minimally Invasive Glaucoma Surgery – A Practical Guide

The treatment of patients with mild to moderate glaucoma has evolved rapidly in the last decade. Traditionally, medical and laser treatments were the mainstay of therapy for this group of patients. Trabeculectomy, non-penetrating surgery and glaucoma drainage implants were reserved...

Long-term specular microscopy following Nd: YAG iridotomy in chronic POAG

The aim of this study was to evaluate specular microscopy of chronic primary angle-closure glaucoma (CPACG) eyes at least one year after Nd:YAG iridotomy, and compare them with CPACG eyes without an iridotomy and age-matched, normal eyes. Nd:YAG laser causes...