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Association between neurodegeneration and macular perfusion in the progression of diabetic retinopathy

In this prospective three-year longitudinal study, the authors aimed to explore the relation between retinal neurodegenerative changes and vessel closure (VC) in individuals with non-proliferative diabetic retinopathy (NPDR). The participants included 74 individuals with type 2 diabetes, NPDR, and Early...

A comparison of colour vision tests in the presence of contrast sensitivity loss

This study analyses the effect of contrast sensitivity (CS) loss on colour vision (CV) testing, using a variety of colour vision tests. The authors used a computer model for CS loss to determine its effect on CV testing scores for...

Bitemporal hemianopsia as a result of ethambutol toxicity

The authors present six cases of visual loss in patients treated with ethambutol for mycobacterium avium complex, including four patients with bitemporal hemianopsia. Two additional patients were undergoing glaucoma monitoring and developed visual field defects with ethambutol treatment, which recovered...

Refractive changes after surgery

A long-term follow-up study was conducted to report power vector analysis of refractive astigmatic changes in a large group of 137 patients (250 eyes) undergoing horizontal strabismus surgery. Fifty-four percent were male. The average age was 9.22±8.21 years. Fifty-five percent...

Three methods of suppression measurement

Test-retest reliability and interchangeability are evaluated for three filter bars available to measure density of suppression: Sbisa bar, Bagolini filter (BF) bar and neutral density filter (NDF) bar. The study involved 10 strabismic adults. Testing conditions were altered and effects...

Resveratrol protects against steroid induced intraocular pressure

Topical and systemic steroid delivery is a very effective treatment for many ocular conditions but is compromised by raised intraocular pressure which in turn leads to death of retinal ganglion cells and irreversible blindness. This is an important consideration with...

IOP measures after intraocular chemotherapy

This study aimed to describe the relationship between intravitreal chemotherapy and IOP in children with retinoblastoma and identify risk factors for pronounced elevations. This was a retrospective study of ten cases (ten eyes) with 17 encounters overall. Mean age was...

Nicotine accelerates diabetes induced retinal changes

This study investigated the influence of nicotine in an experimentally induced diabetic rat model. They used non-invasive high-resolution spectral domain optical coherence tomography (SD-OCT) imaging to provide quantitative information on the temporal alterations of retinal structures at the micrometer resolution...

Effect of voriconazole of vision of healthy volunteers

Voriconazole is a broad spectrum, triazole antifungal agent used for systemic fungal infections. It has a favourable safety profile and is available in both intravenous and oral forms. The commonest adverse drug reactions with voriconazole are changes in visual perception,...

Sleep positions and the effect on IOP

The authors describe a study to determine if sleeping at a 20 degree head up position decreases nocturnal IOP compared with lying supine in patients with and without glaucoma. They recruited 30 patients (60 eyes) 15 with glaucoma and 15...