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2325 results found

Corneal crosslinking in pellucid marginal degeneration

Fourteen studies were included in this first review examining the use of corneal-crosslinking (CXL) to treat pellucid marginal degeneration (PMD). PMD is a bilateral, non-inflammatory corneal thinning disorder characterised by inferior peripheral corneal thinning 1-3mm from the limbus in the...

Cytokine levels in vitreous fluid in patients with pathological myopia

Pathological myopia (PM) is a leading cause of irreversible visual impairment worldwide, and efforts are dedicated to the study of its underlying mechanisms. Axial extension of the eyeball is regulated via a cascade of biochemical molecules that are initiated in...

RPE tears in cases of IPCV

The aim of this study was to investigate the occurrence, characteristics, management and prognosis of retinal pigment epithelium (RPE) tears in patients with polypoidal choroidal vasculopathy (PCV). Medical records of previous cases were reviewed over an eight-year period from a...

Anatomical and functional outcomes following switching from aflibercept to ranibizumab in NARMD

This is a six-month, prospective, single-arm study in the UK and Germany. A total of 100 patients were enrolled (one in the primary failure group, 99 in the suboptimal treatment response group), treated three-monthly intravitreal ranibizumab injections (0.5mg), and then...

Quality of life concerns after uveal melanoma diagnosis

The authors sought to investigate factors associated with Quality Of Life (QOL) after initial diagnosis of uveal melanoma (UM) using prospectively collected data between September 2011-May 2016. They included 201 participants referred for radiotherapy after UM diagnosis by an ophthalmic...

Silicone oil migration presenting as an eyelid cyst

The author presents a single case report of a rare complication of silicone oil tamponade, silicone oil migration, after pars plana vitrectomy. A seven-year-old female, with a history of vitrectomy one year prior for penetrating eye trauma, presented with a...

Multicentre PCO rates in different brands of monofocal intraocular lenses

This was a longitudinal, retrospective cohort study featuring 47,754 (three years) and 20,763 (five years) eyes with age-related (≥65 year) cataract surgeries between 2010-2013 across seven UK ophthalmology clinics. The three- and five-year incidence of posterior capsular opacification (PCO) and...

Atropine treatment for myopia in western countries – rationale

This preliminary study sets out the rationale, methodology and participant baseline characteristics for the Western Australia Atropine for the Treatment of Myopia (WA-ATOM). It is a double masked randomised placebo-controlled trial. This study is designed to be combined with the...

Orbital sphenoid sinus trauma: a rare trauma case

With a high complication and mortality rate, intra-sphenoidal and transorbital trauma poses a high complication rate and remains challenging to manage. Numerous key structures run nearby such as: the optic nerve, internal carotid arteries and ophthalmic arteries. The authors present...

Uveitis‐Glaucoma‐Hyphaemia syndrome retrospective case-control study

The authors present the findings of a case-control study aiming to assess uveitis‐glaucoma‐hyphaemia (UGH) syndrome, focusing on the resolution, glaucoma development and risk factors. The authors compared three groups each containing 71 patients. Each group contained patients with UGH syndrome,...

Retinoblastoma in older children

Retinoblastoma is the most common ophthalmic malignancy in childhood and over 90% are diagnosed before the age of five years. It is not often suspected in older children given its rarity and unusual clinical findings which complicates the diagnosis. The...

Mobile phone use with esotropia development

This study analysed clinical characteristics and surgical outcomes in patients with acquired comitant esotropia (ACET) and determined the prevalence of excessive mobile touch screen device use in these patients. This was a retrospective study of 35 patients of which three...