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OCT changes in chronic optic neuropathy

The authors evaluated optical coherence tomography (OCT) angiography in 10 patients who suffered various types of chronic optic neuropathies. Glaucoma is known to cause a decrease in peripapillary perfused capillary density on OCT angiography. However, other optic neuropathies have not...

Excessive blinking

A case review is presented to understand the clinical implications for children presenting to ophthalmology with episodes of excessive blinking in the absence of any obvious ocular abnormalities. This retrospective review was conducted from 2011-2014. The authors contacted parents and...

Importing iron to the retina

In the retina, iron is particularly critical for the visual phototransduction cascade. In the retinal pigment epithelium (RPE), RPE65 activity leads to 11-cis-retinaldehyde, the photosensitive component of rhodopsin production and iron containing enzymes are necessary for disc replacement in photoreceptor...

A possible biomarker for diabetic retinopathy

Diabetic retinopathy (DR) is the most common form of diabetic eye disease, characterised by exudates, microaneurysms and haemorrhage. Early diagnosis is crucial for preventing visual loss. The risk of developing diabetic retinopathy is known to increase with age as well...

Corneal lenticule allotransplant

This animal study looked at corneal lenticule allograft transplantation in rabbits. Seven rabbits underwent small incision lenticule extraction (SMILE) procedures, where their stromal lenticules were extracted and transplanted fresh into pre-prepared corneal stromal pockets of seven recipient eyes. Animals were...

Surgery for horizontal nystagmus

The authors report two consecutive interventional surgical series in which the authors describe their experience with the Sinskey anterior extirpation procedure (SAEP) and a newly modified myectomy without reattachment (MWR). In a review of 39 patients, 20 underwent the SAEP...

Vitrectomy after ocriplasmin for VVMT adhesion of MH study

This is a multicentre retrospective study of 51 eyes that received intravitreal ocriplasmin between January 2013 to January 2014 for symptomatic vitreomacular (VMT) +/- macular hole (MH), and then went on to PPV for persistent pathology, comparing a control group...

Does cornea cross-linkage reduce the rate of corneal transplants in keratoconus?

Cornea cross-linking (CXL) is a relatively new treatment in the management of keratoconus, which may help prevent the need for corneal transplant. This paper investigates if the introduction of corneal cross-linkage has reduced the number of corneal transplants performed annually...

RCT of operative routes for congenital cataract surgery

The authors evaluated the performance of 25G vitrectomy systems in the management of congenital cataract in infants through two routes – anterior (transcorneal) and posterior (pars plana). This was a prospective randomised trial (RCT) of 24 eyes of 12 patients...

E-Dobson card for visual acuity

The authors assessed the utility of an electronic Dobson acuity card which can be altered for spatial frequency. Thirty-six infants and toddlers aged 5-36.7 months were recruited – equal females and males. Fourteen had high refractive error. The card is...

Visual consequences of congenital hypothyroidism

This study evaluated the frequencies of ophthalmic abnormalities in Turkish children with a history of congenital hypothyroidism in a retrospective study of 121 children. Median age was nine months (one to 216) at initial ophthalmic examination. Forty children were ex-premature...

Predictors of IOP reduction after SLT

The aim of this study was to identify predictors of intraocular pressure reduction following selective laser trabeculoplasty (SLT) in patients with primary open-angle glaucoma, who are already taking maximally tolerated IOP-lowering medication and need further IOP reduction. In this prospective...