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Ethnic disparities in diagnostic sequencing yield

The authors present a systematic review and meta-analysis of the diagnostic yield of next generation sequencing (NGS) for inherited retinal diseases and compare yield from studies performed primarily on patients of European descent from those primarily of East Asian descent....

Immunoglobulin G4-related ophthalmic disease – what is it? (Part 2)

Part 2: Clinical presentation and treatment (see part 1 here) Introduction IgG4-related disease (IgG4-RD) is understood to have a vast clinicopathological spectrum; nearly every organ has had reported involvement. Similarly, IgG4-related ophthalmic disease (IgG4-ROD) is known to affect nearly every...

The tragedy of the commons

I am a big fan of the YouTube channel Extra Credits History, in which interesting historic events are explained in breathtakingly simple detail in 10 animated videos. I have watched every episode, including the ‘Early Christian Schisms’ and ‘The South...

Aug/Sep 2015 Quiz 2

History A two-year-old female child presented with loss of vision in her left eye. Examination showed leukocoria and intraocular calcification was identified on scanning. The suspected diagnosis was intraocular retinoblastoma and the child underwent an enucleation. The eyeball was submitted...

Eye drop reminder apps

There are quite a few apps in both the iPhone and Android app stores designed to help patients remember to take their eye drops. The goal here was to select an app suitable to recommend to patients. Ophthalmic specific apps...

Neonatal hypoxic ischaemic encephalopathy with imaging abnormalities in the occipital lobe – how to counsel the parents

Case A baby boy, with a background of intrauterine growth restriction, was born at 37 weeks and three days gestation via forceps delivery. The baby was born in poor condition, with low heart rate, poor respiratory rate, poor colour and...

Embrace the great outdoors to safeguard eye health, urges world-leading eye surgeon

World-leading eye surgeon, Mr John Bolger, urged global action to address escalating rates of myopia (short-sightedness) among young people when he led a distinguished panel of experts at this year’s International Myopia Conference 2024 in Sanya City, Hainan Province, China....

Canon Medical announces Sense Medical as new UK distributor

Canon Medical Systems Europe today announced that it has signed an agreement with Sense Medical to be the official exclusive distributor of their ophthalmic eye care products within the United Kingdom and Ireland.

Aug/Sep 2017 Quiz

History A seven-year-old atopic boy has been treated for phlyctenulosis with mild topical steroids. However, he developed dramatic changes at the right limbus in two weeks. He also had past history of vernal keratoconjunctivitis (VKC) with poor compliance to treatment....

Applying for ophthalmology ST1 in 2026: What’s new?

Competition for ophthalmology ST1 has intensified steadily over recent cycles, rising from ~9:1 (2022) to ~10:1 (2023), ~14:1 (2024) and ~22:1 (2025) [1]. Against this background, applicants benefit from a structured approach: mapping achievements to portfolio domains early, identifying gaps...

Periocular burns: a literature review of classification, management protocols and outcomes of treatment

The author provides a review of the current literature regarding the principles of classification, management protocols of acute ocular and periocular burns and the role of the burn and oculoplastic surgeon involved in their care. More than two-thirds of facial...

Mad world

The early 1980s were a glorious time to be a teenager. Along with BMX bikes, Airwolf and Quattro, we had a plethora of new music genres to be enthralled by. The band Frankie Goes to Hollywood with their dance /...