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RTP801 as a neuroprotective and axon regenerative treatment
This paper describes the neuroprotective and axon regenerative effects of siRTP801, which is a translatable small-interfering RNA (siRNA) targeting mTOR negative regulator; RTP801, through in-vivo and in-vitro models. In-vivo studies involved an optic nerve crush rat model with intravitreal injections...RNIB and Roche UK launch new eye health audit tool to improve delivery of local eye health services
Leading sight loss charity RNIB (Royal National Institute of Blind People) and Roche UK have today launched a new eye health audit tool: Eye Level.
The evolution and visual prognosis of glial proliferation of different grades after macular hole surgery
This retrospective research study aimed to investigate the evolution of glial proliferation of varying grades after successful idiopathic macular hole repair and its effects on foveal microstructure and best-corrected visual acuity (BCVA). Two-hundred and two eyes were enrolled in this...100% Optical unveils all of the new, returning, and independent brands for 2026 exhibition
Organisers of the UK’s largest optical event, 100% Optical, have announced the official exhibitor list which features top independents, returning names and brands that will be making their 100% Optical debut at the 2026 show. New eyewear and eyecare brands...The ABC tragedies: Part one
“In the midst of tragedy, we start the comedy” – Agatha Christie, The ABC Murders. Throughout a career in medicine, we are often faced with tragedy. One of the coping mechanisms is to use humour to navigate the mini everyday...AI-enabled smart cane scoops award for transforming lives of people with sight loss
An AI-enabled smart cane designed to transform the lives of people with sight loss has won a prestigious international design award. The WeWALK Smart Cane was recognised by the iF International Forum Design at this year’s product design awards. The...
Surgery for horizontal nystagmus
The authors report two consecutive interventional surgical series in which the authors describe their experience with the Sinskey anterior extirpation procedure (SAEP) and a newly modified myectomy without reattachment (MWR). In a review of 39 patients, 20 underwent the SAEP...
Ripasudil after Descemet stripping in Fuch’s endothelial dystrophy
This study prospectively evaluated the use of ripasudil, a rho kinase inhibitor, in patients undergoing Descemet’s stripping only (DSO) without an endothelial graft for Fuch’s endothelial dystrophy (FED). Patients with dense central guttae limited to the central 5mm of the...Refined glaucoma referral practice offers prospect of improved capacity and expanded role for primary eye care professionals
Glaucoma is the most frequent cause of irreversible blindness worldwide and the second leading cause of blindness in the UK [1,2]. The global prevalence of glaucoma in 2010 was approximately 3.5% for people aged 40-80 years, according to Jonas et...Major grant secured to transform immune cell imaging research
A research team has been awarded significant funding by the National Institute for Health and Care Research (NIHR) to develop an innovative drug-device combination that aims to revolutionise how individual immune cells are monitored and treated in patients at Moorfields...Artificial intelligence in eyecare: how do we ensure new technologies truly benefit our patients?
From monitoring patients with heart disease to improving the early diagnosis of cancer, artificial intelligence (AI) using deep learning techniques is already employed in many different healthcare specialties [1]. In the eyecare field, AI technologies have been used to analyse...
