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Gene therapy for inherited retinal disease: the Manchester Ocular Gene Therapy Group MDT service

4 August 2021 | | EYE - Paediatrics, EYE - Vitreo-Retinal, EYE - General
The authors describe the process set up in Manchester for the optimum delivery and assessment of a new gene therapy treatment for patients with RPE65 IRD. Inherited retinal dystrophies (IRDs) are the second commonest cause of severe visual impairment in...
Clinical and Experimental Ophthalmology journal cover image

Microdroplet and splatter contamination during phacoemulsification in COVID-19 era

3 June 2021 | | EYE - Cataract, EYE - Refractive | COVID-19, SARS-CoV-2, aerosol-generating procedure, microdroplet generating procedure, phacoemulsification cataract surgery
Half a millilitre of fluorescein was incorporated into 400ml of balanced salt solution to identify microdroplet and splatter from phacoemulsification to simulate possible COVID-19 contamination. Five porcine eyes were mounted to an ophthalmic mannequin head and two surgeons (height 189cm,...

Optical practices to continue to provide urgent and essential care

25 March 2020
The UK Government has now published further guidance clarifying that opticians are exempt from the general requirement for retail businesses and premises to close. Optical practices may therefore continue to provide urgent and essential eye care to the extent that they can, including remote care, while managing COVID-19 risk to keep patients, staff and the public as safe as possible.

Ophthalmology in the COVID-19 pandemic

5 June 2020 | | EYE - Neuro-ophthalmology, EYE - General
The novel coronavirus pandemic has affected the whole world and forced all of us to think of new ways to manage our day to day personal as well as professional life. I am not going to talk about the clinical...

Optimising an acute eye service in the current COVID-19 crisis

5 June 2020 | | EYE - General
With the current global pandemic of COVID-19 we have all had to redesign and reorganise our normal working practices. Non-urgent hospital work has been postponed to allow redistribution of resources, redeployment of hospital staff and to reduce the risk of...

Resurfacing the ocular surface

1 April 2016 | | EYE - Cornea
The ocular surface (OS) is an anatomical and functional unit made of the tear film, the conjunctival, limbal and corneal epithelium, the lacrimal, mucous and meibomian glands and the lids and blink reflex. The tear film is composed of a...

Radiation retinopathy

5 June 2020 | | EYE - Vitreo-Retinal, EYE - General
The authors review the current treatment options for this condition. Radiation retinopathy (RR) occurs as a complication after exposure to any type of radiation (external beam, plaque brachytherapy and stereotactic radiosurgery) in the orbital or adnexal region. These include nasopharyngeal...

The role of inflammation in the pathophysiology of DMO

1 February 2016 | | EYE - Vitreo-Retinal
Diabetic macular oedema (DMO) is a major cause of visual loss in diabetes, with a complex multifactorial pathogenesis. In the UK alone it is estimated that there are nearly 2.5 million diabetic patients aged over 12 years. Approximately 65,000 of...

Neovascular AMD: fresh recommendations underline standards of best practice

1 December 2013 |
The management of neovascular age-related macular degeneration (nAMD) has advanced dramatically over the past seven years, with the introduction of targeted new therapies that successfully maintain or improve vision in a majority of affected individuals. It’s a fast moving field,...

Management of retinal diseases: highlights from the AAO 2019 Retina Subspecialty Day Meeting

2 December 2019 | | EYE - Vitreo-Retinal, EYE - General
The author highlights current debate, opinion and late breaking developments in the management of retinal diseases. The American Academy of Ophthalmology’s 2019 Retina Subspecialty Day Meeting was held on 11-12 October, 2019 in San Francisco, USA. Established and emerging innovative...

Update on emerging therapies for age-related macular degeneration

4 December 2023 | | EYE - Vitreo-Retinal
The 23rd European Society of Retina Specialists (EURETINA) Congress, held in Amsterdam, the Netherlands, provided a timely update on anti-complement therapy for geographic atrophy and emerging investigational therapies for neovascular age-related macular degeneration. Anti-complement therapy for geographic atrophy Geographic atrophy...

Is patient masking leading to an increase in post-op infection after eyelid surgery?

21 October 2020 | | EYE - Oculoplastic
Due to the COVID-19 pandemic, the use of facemasks or face coverings in the clinical setting has become necessary. It is important to recognise that facemasks can be a source of infection after eye surgery and consider ways to minimise...