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Ophthalmology

Intraocular lens technology to deliver enhanced optical performance after cataract refractive surgery

1 February 2017 | Rod McNeil | EYE - Cataract, EYE - Refractive

Modern cataract surgery aims to provide patients with the best possible visual outcome with the least dependence on spectacles and minimal or no complications and to treat both cataract and refractive errors with a single procedure. Phacoemulsification is the standard...

Do steroids prevent progression to proliferative diabetic retinopathy (PDR)?

1 February 2017 | Usha Chakravarthy (Prof) | EYE - Vitreo-Retinal

There is continuing debate on the merits of pan-retinal photocoagulation (PRP) for severe pre-proliferative and proliferative DR versus the newer therapies that inhibit vascular endothelial growth factor (VEGF). This has been hotly debated [1] following the publication of findings from...

Non-arteritic anterior ischaemic optic neuropathy (NA-AION): a review

1 February 2017 | James F (Barry) Cullen | EYE - Neuro-ophthalmology

Ischaemic optic neuropathy (ION) is the commonest adult optic neuropathy encountered today in our ageing population, is a common cause of irreversible visual loss and is usually associated with underlying vascular disease. The condition is classified as follows: (a) Anterior...

Retinoblastoma management update (part 2): treatment, screening and surveillance, long-term follow-up and new developments

1 February 2017 | Manoj V Parulekar | EYE - Oncology

Retinoblastoma treatment requires significant multidisciplinary input, but early detection through raising awareness remains key to improving outcomes. In the second article of a two-part series, Manoj Parulekar discusses retinoblastoma management, screening and research. This article has been published in two...

Retinoblastoma management update (part 1): clinical features, diagnosis and genetics

1 January 2017 | Manoj V Parulekar | EYE - Oncology

The first of a two part series, this article will discuss the clinical features, diagnosis and genetic aspects of retinoblastoma. Manoj Parulekar is based at Birmingham Children’s Hospital, one of the two designated national retinoblastoma and paediatric ocular oncology treatment...

An update on inherited retinal disorders (part 2): Approaches to therapy for IRDs

1 December 2016 | Stacey Strong, Michel Michaelides (Prof) | EYE - Vitreo-Retinal

Part 1 of this topic can be found here There are currently no proven cures for inherited retinal disease (IRD). However, multiple avenues of research are being investigated to better understand disease mechanisms and trial potential therapies that may slow...

25 years of OCT

1 December 2016 | Taha Soomro, James Talks | EYE - Vitreo-Retinal, EYE - Imaging

David Huang first described optical coherence tomography (OCT) in 1991, in his seminal paper on the subject in Science. This method developed the work of others on ophthalmic interferometry, which essentially showed that measuring reflected light could be used to...

Image of an eye

Sickle cell eye disease: an overview of vitreoretinal complications and their surgical management

1 December 2016 | Antonio Berarducci, Tom Williamson | EYE - Vitreo-Retinal

Sickle cell disease is the most common genetic disorder worldwide and is associated with lifelong anaemia, intermittent pain and multi-organ morbidity. Ocular involvement can be associated with significant visual impairment due to the complications of proliferative sickle retinopathy (PSR). Occasionally...

What’s new in wet AMD papers?

1 December 2016 | Rod McNeil | EYE - Vitreo-Retinal

Paper presentations on neovascular (‘wet’) age-related macular degeneration (AMD) from the 16th European Society of Retina Specialists Congress, Copenhagen, September 2016, outline recent research directions evaluating the impact of vision loss on key health domains, patient preferences in the process...

An update on inherited retinal disorders (part 1) – overview and assessment of inherited retinal disease

1 October 2016 | Michel Michaelides (Prof) | EYE - Vitreo-Retinal

Part 2 of this topic can be found here Inherited Retinal Disease (IRD) is the leading cause of blindness certification in the working age population (age 16-64 years) in England and Wales and the second most common in childhood [1]....

More sensitive visual acuity test for age-related macular degeneration

1 October 2016 | Roger S Anderson (Prof), Nilpa Shah | EYE - Vitreo-Retinal

Age-related macular degeneration (AMD) is the leading cause of blindness in the developed world. Primarily associated with ageing, genetic factors and lifestyle choices such as smoking also play a contributory role. Patients with early AMD, characterised by the development of...

The bionic eye – behind the headlines

1 October 2016 | Rod McNeil | EYE - Oculoplastic, EYE - Orbit

Multiple visual prosthetic projects and other vision regeneration initiatives being tested in preclinical and clinical development worldwide illustrate continuing progress and opportunities in addressing profound blindness from hereditary retinal diseases and other causes (Table 1). Three implantable bionic vision systems...

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