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EEG changes following use of cyclopentolate 1% eye drops

Cycloplegic eye drops may affect the central nervous system. This study reports electroencephalogram (EEG) changes in a cohort of 6–15-year-old children. EEG recordings were taken after placebo and two doses of cyclopentolate 1% in 24 awake children (36 children had...

Ocular ischaemic syndrome in a rat model

Ocular Ischaemic syndrome is a devastating eye disease caused by severe carotid stenosis. This study’s purpose was to develop a reliable rat model for this syndrome by subjecting rats to common carotid artery occlusion and sham surgery. Rats were assigned...

High dose (2.5mg) bevacizumab for postradiation cystoid macular oedema

The authors present a retrospective, interventional case series investigating the efficacy of high dose (2.5mg/0.1ml) intravitreal bevacizumab in the treatment of persistent postradiation (Iodine-125 plaque brachytherapy for uveal melanoma) cystoid macular oedema (CME). Persistent CME was defined as increased or...

Could Twitter boost the impact of ophthalmic journal articles?

*Equally contributing co-first authors. The authors investigate the link between ‘tweets’ and citations for 155 articles from five key ophthalmology journals. Social media’s impact on our lives has been significant, allowing easy discussion of topics worldwide. An increasing number of...

Ologen Collagen Matrix to treat ocular hypotony after filtration glaucoma surgery

The authors report a retrospective, observational case series of a Japanese cohort. 12 consecutive implantations of ologen in nine eyes of nine subjects (five men, four women; mean age ±SD, 72.1±12.7 years) who underwent subconjunctival implantation of the device to...

Regulatory drug evaluations and expedited review initiatives: EU and US perspectives

The European Medicines Agency (EMA) and United States Food and Drug Administration (FDA) each conduct independent assessments of benefit-risk profile when evaluating applications to market new or modified medicines, and their respective decision-making is guided by distinct legislation, procedures and...

Guide to Gaining Approval for a Clinical Study

This article focuses on gaining approval for clinical research involving NHS patients, although the principles can be applied to other types of research. The intention is to give an overview of the requirements for setting up a research study, but...

“Robot performs cataract surgery on patient!”

Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are scientific reality and which are ‘fake news’. Headline: “Robot performs cataract surgery on patient!” Twenty-five years ago when Eye News launched, a news headline such...

Orbis marks 100-millionth antibiotic dose in the fight against trachoma in Ethiopia

Orbis and partners mark historic 100-millionth dose of azithromycin antibiotics in the fight to eliminate blinding trachoma in Ethiopia by 2030. This milestone was achieved 20 years after Orbis began leading mass drug administrations.

Saccadic eye movements in young-onset Parkinson’s disease

The objective of this study was to understand control of saccadic eye movements in patients with young onset Parkinson’s disease (YOPD) where onset of disease symptoms appears early in life (<40 years of age). Functional magnetic resonance imaging (fMRI) was...

Well-presented scholarly research work will reduce chances of journal rebuttal

Submitting to an academic journal? Are you aware of the requirements and constraints of relevant copyright laws? Rod McNeil provides a guide for aspiring authors. Getting published in peer-reviewed academic and medical journals is not easy. But careful attention to...

Rapid Ophthalmology

The book is written by a specialist trainee and as the name suggests is indeed a rapid novice’s guide to ophthalmology. The target audience are the medics and junior doctors who need a brush up or exam revision. However, the...