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647 results found

Brn3b neuroprotective effect in rat glaucoma model

An adeno-associated virus-directed overexpression of the Brn3b protein in hypothesised to confer neuroprotective effects in this paper. This is ultimately tested in a well-accepted rat glaucoma model (Morrison’s model: saline injection into episcleral veins of rat eyes with a force...

Reproducible OCT RNFL map in unilateral glaucoma

The aim of the study was to compare the reproducibility of the optical coherence tomography retinal nerve fibre layer (OCT RNFL) thickness map between glaucomatous and fellow normal eyes of unilateral glaucoma patients. The authors carried out a prospective case...

Effect of refractive corneal surgery on IOP and glaucoma progression

Accuracy of intraocular pressure (IOP) measurement depends on the biomechanical properties of the cornea, including its thickness central corneal thickness (CCT) and keratometry (K). Fifty-six eyes of 56 patients with primary open angle glaucoma (POAG) who had a history of...

Phaco-ECP vs. Phaco alone to treat glaucoma

This retrospective review compared combined phacoemulsification and endoscopic cyclophotocoagulation (phaco-ECP) to phaco alone in patients with mild to moderate glaucoma. Outcome measures included cumulative full and qualified success survival, postintervention IOP and ocular anti-hypertensive medication reduction. Full success was defined...

Trabeculectomy with MMC in post-traumatic angle recession glaucoma

This study aimed to evaluate the outcomes of primary trabeculectomy with mitomycin-C (trab MMC) in phakic eyes with post-traumatic angle recession glaucoma with no prior intraocular surgery. Thirty-two phakic eyes of 32 patients who underwent trab MMC between January-2002 and...

Effects of phacoemulsification on IOP and drug use in glaucoma

For patients with comorbid cataract and primary open-angle glaucoma (POAG), guidance is lacking as to whether cataract extraction and traditional filtering surgery should be performed as a staged or combined procedure. Achieving this guidance requires an evidence-based understanding of the...

Four key questions and answers for glaucoma practitioners

In this discussion paper the authors pose four questions for the clinician diagnosing and monitoring glaucoma, and supply evidence-based answers. Worldwide, the most common functional test used to diagnose and monitor glaucoma is static automated perimetry, most typically with a...

Atlas Optical Coherence Tomography of Macular Diseases and Glaucoma

The book is divided into three sections: an introduction to optical coherence tomography (OCT), the OCT in macular diseases, and glaucoma. The first section lists the currently commercially available OCT machines, then describes the techniques for acquiring OCT images using...

Comparison of methods of central corneal thickness measurement in glaucoma

This prospective study was done to compare the accuracy and reproducibility of central corneal thickness measured by hand-held and disc-mounted ultrasound pachymeter in glaucoma patients. Sixty-five patients were included in the study. Patients with corneal diseases, corneal astigmatism >3 diopters...

Long-term open angle glaucoma cohort study

This was a study to estimate the development of open angle glaucoma (OAG) in a screened and re-examined elderly group as compared to an unscreened group during the same time period. The participants comprised of 856 individuals born in 1915...

Measurement considerations in OCT results with suspected glaucoma

The purpose of this study was to determine retinal nerve fibre (RNFL) thickness parameters and assess the relationship between the cup-to-disc (CD) ratio and RNFL measurements of paediatric patients who had optic nerve appearance suspicious for glaucoma based on enlarged...

Severe conjunctival cicatrisation secondary to chronic glaucoma therapy

The timing of glaucoma filteration surgery during the course of chronic progressive glaucoma remains a contentious issue amongst glaucoma specialists. The vast majority support the use of maximal medical treatment initially to achieve the target pressure. Surgical procedures are only...