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Corneal Collagen Cross-Linking

As the title suggests, this publication provides a single volume that collates much of the current knowledge and application for corneal collage cross-linking (CXL). There are 23 chapters, subdivided into seven sections, including five pages of indices. The chapters are...

Topography based keratoconus progression after corneal collagen cross-linking

Case 1 describes a 35-year-old man with progressive keratoconus (PK). His best corrected visual acuity (BCVA) was right 20/80 (-5.25/-7.75 x 85) and left 20/20 (+4.75/-5.00 x 90). His Ks were right 36.32/48.02 D and 41.15/46.41 D. Right central cornea...

High-fluence collagen cross-linking

The authors treat seven eyes with progressive keratoconus with a high energy (18mW) for five minutes delivering a total energy similar to that suggested by the original Dresden protocol (3mW for 30mins). All eyes had a thickness >400µm following epithelial...

Conventional vs. accelerated cross-linking

The Dresden protocol of 3mW/cm2 irradiance for 30 minutes has been extensively studied and has shown advantageous clinical and topographical results. However, this protocol is time-consuming and therefore accelerated CXL using higher irradiance to shorten treatment duration has emerged. The...

Results of corneal cross-linking in very steep corneas

Corneal cross-linking (CXL) has been shown to be a safe and valid treatment option for progressive keratoconus and have shown an arrest of progression with a low failure rate of 0% to 2.8% in mild to moderate keratoconus. A Kmax...

Long-term results of cross-linking treatment for keratoconus

The authors report on the long-term outcomes in a prospective case series of patients with keratoconus undergoing corneal collagen cross-linking (CXL) treatment. Thirty-two patients (40 eyes; mean age 22.5+/-5.5 years) with Grade I, II and III progressive keratoconus were recruited...

Accelerated (9mW/cm2) corneal collagen cross-linking for keratoconus

This is one of many studies published / to be published on corneal collagen cross-linking that has a treatment time of 10 minutes compared to the previous Dresden protocol of 30 minutes to halt progression of keratoconus. Much has changed...

Corneal cross-linking for treatment of corneal ulcers

This was an observational cohort study looking at the usefulness of photo activated chromophore for infectious keratitis-corneal collagen cross-linking (PACK-CXL) in reducing the time to heal in suppurative corneal ulcers. This study, conducted in a tertiary care centre in South...

Repeat corneal collagen cross-linking after failure of primary cross-linking (CXL) in keratoconus

This is a 10-year, retrospective, patients record review from Leeds, UK. Twenty-one eyes had repeated CXL and the mean interval between primary and repeat CXL was 47.1 months. Twenty (95%) eyes stabilised after repeated CXL at a mean follow-up of...

Bandage contact lens cultures after corneal collagen cross-linking

Corneal collagen cross-linking (CCL) is a treatment modality that has been shown to stop the progression of keratoconus. There have also been reports that CCL acts as an antimicrobiologic agent in treating resistant microbial keratitis. This study aimed to investigate...

Outcomes of corneal cross-linking in paediatric patients compared to fellow untreated eyes

This retrospective cohort study evaluated long-term visual, refractive, topographic and safety outcomes of corneal cross-linking (CXL) in patients younger than 18-years-old with keratoconus. The study included all consecutive paediatric patients who underwent epithelium-off CXL treatment for keratoconus at the study...