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373 results found

Presentation of conjunctival intraepithelial neoplasia

Ocular surface squamous neoplasia is the umbrella term for malignancies of the conjunctiva and within the spectrum lies conjunctival intraepithelial neoplasia (CIN) – a non-invasive malignancy. CIN has been implicated with ageing, smoking and ultraviolet light exposure. The typical manifestation...

Conjunctival inflammation in glaucoma patients

Numerous studies have demonstrated that topical medications and preservatives used for the management of glaucoma can induce significant histopathologic and inflammatory changes in the ocular surface. This study describes an increased expression of major histocompatibility complex class II antigen HLA-DR,...

Conjunctival mapping biopsies in sebaceous carcinoma

This is a retrospective review of conjunctival mapping biopsies in patients with periocular sebaceous cell carcinoma. The authors reviewed the biopsy technique and outcomes of 45 patients who had mapping biopsies performed over a 25-year period. A total of 429...

A tarso-conjunctival flap for paralytic ectropion

This is a review of 110 patients with paralytic ectropion who underwent a lateral tarso-conjunctival flap procedure. The technique involves fashioning a 4-8mm wide lateral tarso-conjunctival flap in a similar way to a lateral Hughes flap. This is then sutured...

Severe conjunctival cicatrisation secondary to chronic glaucoma therapy

The timing of glaucoma filteration surgery during the course of chronic progressive glaucoma remains a contentious issue amongst glaucoma specialists. The vast majority support the use of maximal medical treatment initially to achieve the target pressure. Surgical procedures are only...

5-FU vs. Avastin as adjunct to conjunctival autograft

The authors compare the outcome of pterygium treatment using 5-fluorouracil as an adjunct to free conjunctival autograft versus bevacizumab (Avastin) as an adjunct to free conjunctival autograft, via a randomised controlled prospective study. Seventy eyes of 70 patients were included...

Conjunctival melanoma involving the lacrimal drainage system

A total of 52 patients were diagnosed with conjunctival melanoma over a period of 17 years, 17 of whom required orbital exenteration. Five of these were found to have melanoma involving the lacrimal drainage apparatus (LDA). One was evident clinically...

Squamous metaplasia of conjunctival epithelial cells with soft contact lens wear versus non-lens wearers

Conjunctiva is composed of non-squamous epithelial cells interspersed with goblet cells, which is a secretory epithelium. Squamous metaplasia is a transformation to non-secretory epithelium, ‘keratinised’ and enlargement of the conjunctival non-goblet cells and relatively shrunken nuclei are seen on impression...

Amnion-assisted conjunctival epithelial redirection (ACER): Enhancing stem cell transplantation treatment of total limbal stem cell deficiency

An exploration of Professor Harminder Dua’s recent work using a technique called amnion-assisted conjunctival epithelial redirection (ACER) to aid the success of conjunctival-limbal grafting procedures. ACER provides a refined way to use amniotic membrane (amnion), such as Omnigen® (NuVision® Biotherapies,...

Feb/Mar 2015 Quiz 2

History A 60-year-old white Caucasian male, with a history of acne, presented with slate grey pigmentation of his upper forehead, pre-auricular skin, peri-oral area, forearms and shins. The conjunctivae showed bilateral lower tarsal conjunctival multiple black dots. One of these...

Allergic conjunctivitis evaluation by thermography

Thermography is a non-invasive imaging technique, which uses infrared radiation reflected from an object to estimate the temperature of the object. This paper evaluates the use of thermography to assess allergic conjunctivitis objectively, by using an instrument called ocular surface...

Conj reconstruction with amniotic membrane

This study reports the use of amniotic membrane in patients with restrictive strabismus or conjunctiva problems during or following complex eye muscle surgery. Ambio 5 was used for replacement of conjunctiva in this retrospective study of 32 cases aged one...