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Adjuvant oral voriconazole or oral ketoconazole for fungal keratitis
This randomised double-blinded trial examined clinical outcomes of 50 patients with severe fungal keratitis treated with either adjuvant oral voriconazole or oral ketoconazole. Inclusion criteria were culture or smear proven fungal ulcers >5mm in maximum diameter, involving >4mm of the...
Silicone hydrogel contact lenses versus autologous serum drops for dry eyes in Sjörgen syndrome
A total of 37 patients with Sjörgen syndrome (SS) related dry eyes reporting symptoms on standard therapy with artificial tears and anti-inflammatory drops were evaluated in this trial. They were randomly assigned to additional treatment with either balafilcon A silicone...
Aflibercept, bevacizumab or ranibizumab for diabetic macular oedema
Macular oedema (MO) is a leading cause of visual impairment in patients with diabetic retinopathy. Whilst laser photocoagulation therapy has been the proven treatment for decades, studies over the last five years have also established a role for anti-VEGF agents...Sustainable prevention of blindness from diabetic retinopathy through prevention and control of diabetes mellitus – LINK partnership experience in Dominica
The Caribbean Diabetic Retinopathy Project (DR Caribbean) is a five-year project that aims to reduce blindness due to diabetic retinopathy (DR) across four Commonwealth countries: Belize, Dominica, Jamaica and St Lucia. The VISION 2020 LINKS Programme at the London School...Dr Glaucomflecken: Stayin’ Alive
Peter Cackett spoke to ophthalmologist and social media sensation Dr Glaucomflecken about his early days in comedy, the role satire can play in impacting medical governance, and where he might take his brand of medical comedy next. It was towards...
Tetracaine to reduce OCR
This study investigates the effects of Tetracaine eye drops on oculocardiac reflex (OCR) during strabismus surgery. A randomised controlled trial of 70 strabismus surgery patients aged two to 19 years was conducted with comparison of Tetracaine versus placebo. Demographics were...
Lagophthalmos as a potential complication of COVID-19
Lagophthalmos is a condition associated with the inability to close the eyelids effectively, with the main cause being facial nerve palsy. The authors aimed to investigate whether lagophthalmos was associated with coronavirus infection (COVID-19) by comparing patients diagnosed with lagophthalmos...
Complement factor B polymorphism and the phenotype of early age-related macular degeneration
The relationship between complement factor H (CFH) and age-related macular degeneration (AMD) is very well known, but other genetic polymorphisms relating to AMD are more poorly understood. This study was designed to investigate the relationship between complement factor B (CFB)...
A relationship between central serous retinopathy and obstructive sleep apnoea
This prospective study aimed to evaluate a relationship between central serous retinopathy (CSR) and obstructive sleep apnoea (OSA). Twenty-three subjects (six female and 17 male) were diagnosed with CSR and overnight polysonography was performed to record desaturation and apnoeic episodes....Troubleshooting in LASIK
Contemporary laser in situ keratomileusis (LASIK) is safe and effective. It remains the dominant intervention in routine refractive surgery for a good reason: predictable results, rapid visual recovery, and relatively simple strategies for revision treatment. Over 95% of patients are...
