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2242 results found

Characteristics of cherry red spot on optical coherence tomography

In this study the authors report optical coherence tomography (OCT) characteristics of cherry red spot from three cases of Tay-Sachs and one case of Niemann Pick diseases to determine associated factors and potential visual implications. This was a retrospective case...

Updated staging of LCHADD retinopathy

The authors present their proposal for an updated staging system for Long-Chain 3-Hydroxyacyl-CoA Dehydrogenase (LCHAD) deficiency retinopathy. This is a rare mitochondrial disease due to deficiency of the long chain fatty acid oxidation pathway. Forty patients who were part of...

Stargardt disease in a Turkish cohort

The authors present a study of 27 Turkish patients who were seen in a single centre over a five-year period. All patients had macular optical coherence tomography (OCT), colour fundus photography and 30-2 Humphery visual fields performed, along with clinical...

Anti-myelin oligodendrocyte glycoprotein antibody positive optic neuritis: a retrospective medical records review

Optic neuritis causes acute loss of visual function and can result in devastating visual dysfunction. Recently, measurements of anti-aquaporin 4 (AQP4) and anti-myelin oligodendrocyte glycoprotein (MOG) antibodies have become available, making it possible to evaluate the disease pathogenesis. This paper...

Longitudinal findings in children with neurofibromatosis type 1

This retrospective chart review evaluates the ophthalmologic findings of children with neurofibromatosis type 1 (NF1). Optic pathway gliomas (OPGs) are the most common tumours found in children with NF1. Findings are compared between eyes with and without optic pathway gliomas...

A novel parameter for angle closure

This is a population cross-sectional study of 464 eyes that underwent swept-source optical coherence tomography (SSOCT) imaging in the dark. Eight out of 128 cross-sectional images were selected for analysis. Matlab was used to measure the iridolenticular contact area (ILCA),...

Infliximab in treatment of PVR

In this phase 2 randomly controlled trial, 66 patients with primary rhegmatogenous retinal detachment and grade C proliferative vitreoretinopathy (PVR) were randomised in a 1:1 ratio to undergo pars plana vitrectomy (PPV) and silicone oil (SO) injection with or without...

How the thinking machine is transforming the retinal landscape

Regulatory approval of the first two therapeutic substances for the management of geographic atrophy (GA) secondary to age-related macular degeneration has been a major breakthrough. The authors explored the issue surrounding the lack of agreed therapeutic standards and diagnostic tools...

Systematic review of management options for intermittent exotropia

The authors conduct a robust systematic review of the literature to report evidence on non-surgical and surgical treatment options for intermittent exotropia – divergence excess and basic intermittent exotropia types. Discussion centres on (1) optical correction of refractive error with...

Corneal surface astigmatism changes after lateral rectus surgery

This prospective study evaluated astigmatic changes in children following lateral rectus surgery. The fellow unoperated eye was used as the control for assessment of anterior and posterior corneal surfaces. The study included 37 patients (74 eyes); 16 male, 21 female...

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Eye News April/May 2022

From Dye to Digital: Why OCTA is replacing invasive imaging in retinal care

For decades, retinal imaging has relied on invasive dye based techniques to visualise the eye’s vasculature. However, Optical Coherence Tomography Angiography (OCTA) is fast becoming the preferred modality, replacing fluorescein and ICG angiography in many clinical settings. As highlighted by...