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Effect of preservative free fluoroquinolones on human corneal epithelial cells in vitro

Fluoroquinolones, including second generation (ofloxacin and ciprofloxacin), third generation (levofloxacin and tosufloxacin) and fourth generation (gatifloxacin and moxifloxacin), are a group of bactericidal agents used to treat multiple ocular infections. The third and fourth generation fluoroquinolones have enhanced Gram-positive activity...

Meibomian gland alteration in patients with primary chronic dacryocystitis: An in vivo confocal microscopy study

Chronic dacryocystitis affects tear film functionality and can predispose to ocular surface disease, however the specific effect of chronic dacryocystitis on meibomian gland function has not been studied. This group therefore performed in vivo confocal microscopy in 28 patients’ eyes...

Saccadic differences under cover test

Patients with intermittent exotropia and exophoria plus ortho subjects underwent measurement of saccadic reaction times (SRTs) to compare those occurring in one eye and those occurring with alternating cover tests (ACTs). Twenty-five subjects were studied. Results for the intermittent exotropia...

Strabismus and surgery impacts on reading

The authors compared eye movement performance during reading in strabismic children without amblyopia and in non-strabismic age-matched children in addition to evaluation of potential effect of strabismus surgery. They studied nine children aged 11-15 years; mean 12.9±0.6 years. Ten healthy...

Biometry measure after cycloplegia

The authors investigated optical biometry in an Indian paediatric population on normal and cataract paediatric eyes and studied the effect of cycloplegia on different parameters measured in these eyes. This was a prospective study of 76 eyes aged five to...

From stereoblind to stereopsis

This study sought to examine the postoperative stereopsis in stereoblind patients with normal or corrected visual acuity. Twenty patients (10 female / male) with an average age of 25.35±6.34 years were studied with primary horizontal comitant strabismus (14 exotropia, six...

Treatment efficacy of stage 4 ROP

This study aimed to determine the efficacy of combined vitrectomy and anti-VEGF injection for advanced stage 4 ROP with extensive neovascular proliferation (NF). The study included nine infants; six bilateral and three unilateral. Seven were female and the mean gestational...

Risk factors for visual impairment in facial nerve palsy

Facial nerve palsy (FNP) is known to be associated with corneal exposure due to the nature of the condition, but how many of those will go on to develop severe visual impairment (SVI)? This study investigates the risk factors associated...

Visual acuity outcomes after cataract surgery in type 2 diabetes (NIDDM): the action to control cardiovascular risk in diabetes (ACCORD) study

This is a retrospective case-control study of 1136 eyes enrolled in the 784 ACCORD patients receiving cataract surgery between 2001-2014. 362 / 1136 eyes had gradable fundus photography for diabetic retinopathy (DR). Seven hundred and sixty-two eyes (67.1%) achieved 20...

Changes in extraocular muscle after the Faden procedure – animal histopathology model

The authors studied the histological changes in the anterior part of the posterior fixation suture including the myoscleral junction, after the Faden operation in eight rabbits. The Faden operation was undertaken in one eye and the fellow unoperated eye served...

Retrospective analysis on the outcomes of contact lens-associated keratitis in a tertiary centre

This is a retrospective cohort study of 161 eyes (153 patients) with contact lens-associated keratitis (CLAK) from Moorfields Hospital between 1 July 2021 to 28 February 2022. They were classified into three groups based on the size of the epithelial...