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Inhibiting high-risk corneal allografts

The cornea is an immune privileged site and as such corneal transplants are very successful. However, in situations where this privilege is lost the failure rises substantially. To combat rejection inhibition of the immune responses depends on steroids and other...

Characteristics of limbal lymphatic vasculature on confocal microscopy

This ex vivo study aims to describe the morphological characteristics of the human limbal lymphatic vasculature using confocal microscopy and immunofluorescence. Twelve corneal specimens are obtained from human donor eyes. These corneal buttons are not suitable for transplantation due to...

Review of pathogenesis of Acanthamoeba keratitis

In this review, the author summarised the current microbiomic and immunological evidence related to the pathogenesis of Acanthamoeba keratitis (AK). AK has been described for almost 50 years, but the exact biology of the disease remains perplexing. Acanthamoeba spp. are...

Treatment and outcomes for Peters anomaly (PA)

The purpose of this study was to evaluate the experience of patients with Peters anomaly (PA) and their treatment results. The study reviewed records of 27 patients (32 eyes); 74% male. Treatment included medical follow-up, optical iridectomy and penetrating keratoplasty...

Customised orbital implants

This is a literature review of the outcomes of orbital fracture repairs using custom-made orbital implants. Customised implants were manufactured in one of three ways, all using a 3D printer; manual moulding of an implant based on a 3D-printed model...

Ocular surface and meibomian gland changes in cicatricial conjunctival disease

The authors evaluate long-term structural and functional meibomian gland and lid margin changes in a retrospective study of 64 patients (64 eyes) with chronic cicatricial conjunctival diseases (CCDs), including ocular cicatricial pemphigoid (OCP; n=22), Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS-TEN; n=24),...

Reducing postop nausea and vomiting

This study adopted an aggressive prophylactic anti postoperative nausea and vomiting (PONV) regime with retrospective review of patient outcomes. Of 794 adult strabismus procedures, 31 (4%) had PONV. Median post-anaesthetic recovery was 45 minutes. Prolonged recovery was associated with long-term...

Eyebrow reconstruction

This article is a systematic review of surgical techniques for reconstruction of the eyebrow. The authors discuss the anatomy of the eyebrow, structure of its hair follicles and principles underlying the reconstruction. Options for direct closure, types of advancement and...

Neurotrophic keratitis

The authors present an overview of the aetiology, diagnosis, current and future management options of neurotrophic keratitis. This is a degenerative corneal disease that occurs following the compromise of trigeminal innervation, leading to hypoesthesia and / or anaesthesia. The aetiology...