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Transcriptomic and regulatory gene associations in open angle glaucoma
The authors report a study utilising a publicly available whole exome sequencing dataset of 28 patients with primary open angle glaucoma (POAG) and seven healthy control patients, and a transcriptomic dataset from the trabecular meshwork of four POAG patients and...Diabetes and diabetic retinopathy: Changes in understanding of the disease over the last 25 years and how the UK is helping low-income countries tackle the challenges
Diabetes – a historical perspective Diabetes mellitus (DM) is a chronic disease caused by inherited and / or acquired deficiency in production of insulin by the pancreas, or by the ineffectiveness of the insulin produced. Such a deficiency results in...Designing ophthalmology services - Part 1: How do we address the queues in a clinic?
This first of a three-part series shows how systems engineering can be used to correctly diagnose and address the causes of delays in a clinic. The second article, which will be featured in the April/May 2020 issue, describes how to...Applying for ophthalmology ST1 in 2026: What’s new?
Competition for ophthalmology ST1 has intensified steadily over recent cycles, rising from ~9:1 (2022) to ~10:1 (2023), ~14:1 (2024) and ~22:1 (2025) [1]. Against this background, applicants benefit from a structured approach: mapping achievements to portfolio domains early, identifying gaps...Glaucoma UK announces winners of the 2025 ‘Excellence in Glaucoma Care Award’
Glaucoma UK is delighted to announce the winners of this year's Excellence in Glaucoma Care Awards – Patrick (Paddy) Gunn from Manchester and Alex Gage Family Optometrists in Sheffield. This annual award celebrates individuals or teams who have made remarkable...Dec/Jan Quiz 2014
History A 25-year-old West African male presents with oral candidiasis, generalised lymphadenopathy and a red nodule in the left upper eyelid. This is biopsied. See histology images. Figure 1. Figure 2. Figure 3. Questions 1. Describe Figure 1 (haematoxylin and...
A standardised strategy for uveitis etiological diagnosis
This was a prospective, non-inferiority, multicentre randomised control trial, which aimed to assess the effectiveness of a standardised approach in the etiological diagnosis of uveitis versus an open strategy, where clinicians could perform any test. The authors developed their standardised...
