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An update on inherited retinal disorders (part 2): Approaches to therapy for IRDs

1 December 2016 | | EYE - Vitreo-Retinal
Part 1 of this topic can be found here There are currently no proven cures for inherited retinal disease (IRD). However, multiple avenues of research are being investigated to better understand disease mechanisms and trial potential therapies that may slow...

Could the sclera be key to glaucoma?

1 December 2017 | | EYE - Glaucoma
The glaucomas are a group of conditions characterised by optic neuropathy and associated visual field defects. Of these, chronic open-angle glaucoma (COAG) – diagnosed on the basis of progressive structural changes to the optic nerve head (ONH) and nerve fibre...

What not to miss in neuro-ophthalmology Part 2

1 August 2018 | EYE - Neuro-ophthalmology
As mentioned previously there are several conditions in neuro-ophthalmology that should not be missed by the general ophthalmologist as well as ophthalmology trainees. We discussed in the first part some of these conditions including third cranial nerve palsies, giant cell...

End stage glaucoma management

1 August 2014 | | EYE - Glaucoma
A 48-year-old female has had multiple drug treatment for glaucoma and is still losing field of vision. How do you manage this over time? This patient is at high-risk for going blind and should be managed aggressively to protect remaining...

Supranuclear ocular motility disorders

1 June 2022 | | EYE - Neuro-ophthalmology, EYE - General
Figure 1: Bilateral INO Introduction Complex ocular motility disorders are a diagnostic challenge. These patients come with very complex ocular motility presentations and require a careful and detailed assessment in order to find the correct diagnosis and arrange appropriate investigations....

The role of aspirin in the treatment of NAION: Benefits and controversies

4 December 2024 | | EYE - Neuro-ophthalmology
Non-arteritic anterior ischaemic optic neuropathy (NAION) is the most common acute optic neuropathy in individuals over 50 with estimated prevalence of 2–10 per 100,000 people, characterised by sudden, unilateral vision loss due to ischaemic injury to the optic nerve head....

The results of the last survey Jun25

2 June 2025 | | EYE - Cataract, EYE - Cornea
The first question refers to whether we check blood glucose levels prior to cataract surgery. Almost three quarters of you do which was interesting. We know that poor glycaemic control (manifesting as a raised HbA1c) has implications for wound healing...

Acute dellen formation post trauma

1 January 2016 | | EYE - Cataract, EYE - Cornea, EYE - General, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal
Corneal dellen are saucer-like thinnings, usually of the peripheral cornea [1]. Dellen formation is thought to be related to localised tear film instability [2], specifically the absence of the mucin component of the tear film. Without the mucin layer, dry...

A step-by-step approach to the diagnosis and management of Sands of Sahara Syndrome

1 October 2018 | | EYE - Cornea, EYE - Cataract, EYE - Refractive, EYE - General
Sands of Sahara syndrome (diffuse lamellar keratitis) is a rare postoperative complication of Laser in situ keratomileusis (LASIK). Its estimated prevalence is reported to be 2-4% among LASIK cases [1], despite that, it is more likely to be encountered by...

Behind the eyes: Unravelling the mystery of a painless progressive proptosis

4 February 2025 | | EYE - Oculoplastic, EYE - Orbit, EYE - Pathology
Orbital fungal infections have the potential to give rise to serious complications. While these infections typically originate in the sinuses, patients may initially exhibit ocular symptoms. As a result of the diverse and often vague clinical manifestations (especially during the...

Cataract incidence rates in patients from the UK suffering with diabetes mellitus

1 October 2018 | | EYE - Cataract, EYE - Refractive, EYE - General
The authors summarise the main findings from a recent study which investigated the incidence rates of cataract in patients with or without diabetes mellitus (DM). Background to the study Worldwide, the World Health Organization (WHO) estimates that 253 million people...

My Top Five: Ophthalmology learning tools for doctors

2 August 2024 | | EYE - General
Starting a career in ophthalmology can be both exciting and demanding. Despite its captivating and broad nature, ophthalmology often proves challenging for beginners around the globe due to limited exposure during medical school [1–5]. Fortunately, plenty of resources are available,...