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Sub-clinical detection methods in multiple sclerosis

Visually symptomatic multiple sclerosis (MS) provides only part of the required information to assist in understanding the disease. Recently, researchers have concentrated their efforts on diagnosing MS cases in the subclinical period. The aim of this paper was to assess...

Reflections on a twelve-year partnership: The Makassar-Dundee LINK

In the first article of a two-part series (see Part 2 here), the authors provide an overview of this hugely successful partnership and how they overcame the challenges of COVID-19. What began in 2008 as a connection between equals, has...

The impact of obstructive sleep apnoea monitoring functionality on smartwatches: a new frontier for ophthalmologists

Dawn of a new era in wearable technology? Smartwatches have really stepped up their game and have evolved from telling time to keeping an eye on our health. In February 2024, the United States Food and Drug Administration (FDA) gave...

Acetylcholine receptor antibodies in the diagnosis of ocular myasthenia gravis at the Manchester Royal Eye Hospital

Myasthenia gravis (MG) is the commonest autoimmune condition to affect the neuromuscular junction. In the UK, its prevalence is 15 per 10,000 [1,2] and recent studies have shown that rates are steadily increasing [3,4]. Aims of this audit The aim...

Rituximab as an immunosuppression treatment for thyroid eye disease

Thyroid eye disease is traditionally treated with high dose glucocorticosteroids and surgical orbital decompression, where responses are often inadequate. This medical treatment is centred around symptom control and reduction of thyroid hormone synthesis, not immunosuppression. Rituximab is an anti-CD20 monoclonal...

The impact of collagen crosslinking on keratoplasty numbers in keratoconics

A question of corneal cross-linking (CXL) reducing keratoplasty numbers in keratoconics was addressed in this single centre observational study from the Oslo University Hospital – a sole provider of keratoplasties and CXL for a population of 2.8 million. Authors compared...

Use of Bagolini filter bars

The authors measured the percentage light transmission of filters on different Bagolini filter bars to evaluate whether a difference exists in density of suppression or strength of abnormal binocular single vision (BSV). A Sekonic dual spot photometer was used to...

Impact of amblyopia on adult planning and problem solving

This study sought to evaluate whether monocular amblyopia has an impact on planning and problem solving in the adult population. The authors used the Tower of London (TOL) test to address this question. The TOL test was developed to assess...

Disc-fovea angle measurements for objective cyclotorsion review

The author measured the disc-fovea angle (DFA) in 249 healthy people (81 male, 168 female) as part of a retrospective study of 44 to 70-year-old adults. These were grouped as (1) aged 44 / 45 years, (2) aged 59-70 years,...

Eye Surgery in Hot Climates (Fourth Edition)

The Fourth Edition of Eye Surgery in Hot Climates by William Dean and John Sandford-Smith has made a debut at a time when there is a surge of interest in global ophthalmology amongst novices and experts alike. Both authors have...

Tumour deposits following choroidal melanoma treatment

The authors present the unique case of retinoinvasive melanoma following treatment of choroidal melanoma with brachytherapy. Uveal melanoma, the commonest intraocular malignancy in adults, presents as a pigmented mass in the choroid, ciliary body, or iris. A 79-year-old Caucasian male...

Investigation of PAX7 positive satellite cells in extraocular muscle surgery

PAX7 is a transcription factor and is expressed in non-active and activated satellite cells. It is needed for muscle progenitor function, survival and expansion. This study investigates the effect of recession/resection surgery on PAX7-positive satellite cells in extraocular muscles of...