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Differential inhibition of EAU by CTLA4 and IL-6

Cytotoxic T lymphocyte antigen-4 (CTLA4) binds both CD80 and Cd86 and inhibits T lymphocyte activation via CD28. Il-6 is a pleiotropic cytokine that has been associated with many autoimmune conditions including uveitis. Blockade of these molecules by either CTLA4-Ig, a...

Is lens constant optimisation for IOLMaster indispensable in order to achieve a good refractive outcome?

A study of refractive outcomes following cataract surgery was carried out with the aim of comparing the postoperative refractive outcomes against Royal College of Ophthalmologists standards and to determine the extent of association between accuracy of intraocular lens (IOL) power...

Does intravitreal bevacizumab help in diabetic retinopathy related vitreous haemorrhage?

This retrospective, interventional case series, aimed to assess the effectiveness of intravitreal bevacizumab (IVB) in vitreous haemorrhage secondary to proliferative diabetic retinopathy. The primary outcome was the rate of vitrectomy (PPV) after IVB, with secondary outcomes the number of IVB...

Community Eyecare Services in Northern Ireland: putting the patient at the centre, improving outcomes and maximising system resource

The UK has four healthcare systems; Northern Ireland, Scotland and Wales each has autonomous legislature that develops health policy, while the UK government directly runs England’s NHS. Like the other nations, Northern Ireland is continually challenged to meet the needs...

Diary from my elective: a Parisian experience

The author explains how a research institute’s dedication to multidisciplinary collaboration helped him to discover a passion for academic ophthalmology. The elective aspect to the final year of a medical degree, through its change of scenery and immersion into another...

Bitemporal hemianopsia as a result of ethambutol toxicity

The authors present six cases of visual loss in patients treated with ethambutol for mycobacterium avium complex, including four patients with bitemporal hemianopsia. Two additional patients were undergoing glaucoma monitoring and developed visual field defects with ethambutol treatment, which recovered...

How to survive the fluorescein round

One of the highlights of the medical retina fellowship programme at Moorfields is the Tuesday morning 8am fluorescein round. It is both exhilarating and terrifying. Exhilarating because they are slick presentations of the most interesting cases that each of the...

Part 1: The Arclight Project – Frugal tech for sight

Click here for Part 2 on this topic, and here for Part 3 The Arclight Project is a mix of frugal design, manufacturing, distribution, teaching, research, and advocacy, all wrapped up in a social enterprise based at the University of...

Thomas Truckenbrod awarded for his outstanding contribution to the optical profession

The International Opticians Association (IOA) has given Thomas Truckenbrod a special award recognising his outstanding contribution to the optical profession. The award was presented by IOA director of development Elaine Grisdale at the SILMO d’Or ceremony on Saturday 30 September in Paris.

ROPScore for detection of any and severe ROP

ROPScore is a free tool consisting of a logistic regression equation to calculate the risk per child and calculated one time per infant at six weeks of life. It helps to predict severe retinopathy of prematurity (ROP). This study aimed...

Reporting the development and pilot use of fixable surgical instruments

This study reports the development of instruments to substitute traction sutures during strabismus surgery and to act in place of surgical assistance. Three types of instruments were developed: (1) fixable multi-functional forceps; (2) fixable muscle hook; and (3) fixable retractor....

Ciliatech presents preliminary results on treating glaucoma with CID at Ophthalmology Futures Symposium

Ciliatech presents preliminary one-year study results on treating open- and narrow-angle glaucoma with CID at Ophthalmology Futures Symposium.