You searched for "regenerative"
A new observation point: updating the nomenclature and classification with OCT
The evolution of ophthalmic imaging technologies has been particularly rapid over the last few years. The author provides an update of the current terms for common signs and pathologies observed using optical coherence tomography. My experience as an ophthalmic technician,...
Corneal lenticule allotransplant
This animal study looked at corneal lenticule allograft transplantation in rabbits. Seven rabbits underwent small incision lenticule extraction (SMILE) procedures, where their stromal lenticules were extracted and transplanted fresh into pre-prepared corneal stromal pockets of seven recipient eyes. Animals were...
Surgical outcomes in third nerve palsy
The authors of this article explore the factors associated with successful surgical outcomes in third nerve palsy, which is known to be difficult to treat. A number of case notes were reviewed for patients who underwent surgery or botulinum toxin...
Switchover study from Botox to Xeomin for facial dystonia
This study carried out in the UK compared the clinical effectiveness and efficiency of switching patients from Botox® injections to Xeomin®. This was carried out in 20 essential blepharospasm, 12 hemifacial spasm and six aberrant facial nerve regeneration patients. Patients...
The risk factors associated with isolated microvascular third nerve palsy
The authors used the Rochester Epidemiology Project for this retrospective case review of third nerve palsy. Inclusion criteria was adults >18 years, with new onset isolated microvascular third nerve palsy diagnosed within a 36-month period, with recovery or significant improvement,...
Investigation of PAX7 positive satellite cells in extraocular muscle surgery
PAX7 is a transcription factor and is expressed in non-active and activated satellite cells. It is needed for muscle progenitor function, survival and expansion. This study investigates the effect of recession/resection surgery on PAX7-positive satellite cells in extraocular muscles of...Corneal confocal microscopy: A window into peripheral nerve health
This article has been verified for CPD. Click the button below to answer a few short questions and download a form to be included in your CPD folder. Corneal confocal microscopy (CCM) is an advanced, non-invasive imaging technique that has...
How many injections in nAMD: ranibizumab vs. aflibercept
Intravitreal anti-VEGF injections make up a large proportion of the workload in ophthalmology clinics. Since the introduction of aflibercept with eight weekly injections there has been an option to use a treatment which may require less treatment, with potential cost...
Is an increased homocysteine level associated with greater risk of AMD?
Basic research studies have implicated homocysteine in causing vascular endothelial dysfunction and inflammation, and this has been borne out in large observational studies which suggested that elevated homocysteine is associated with increased risk of cardiovascular disease. In order to determine...
Ranibizumab for the treatment of age-related macular degeneration
This multicentre randomised prospective open label study compared 0.5 versus 2mg of ranibizumab in patients with submacular retinal pigment epithelial (RPE) detachment due to age-related macular degeneration. Four treatment regimens were used for the two strengths either monthly for 12...
Detection of antiranibizumab antibodies in exudative AMD
In this study the authors aimed to detect immune response to ranibizumab treatment in wet age-related macular degeneration (AMD). An ELISA was employed to quantify the anti-ranibizumab titre which was compared against the control anti-abciximab titre. Titres of anti-ranibizumab antibodies...
