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MicroRNAs in cataract

In an ageing population cataract formation is one of the leading causes of blindness. Cataracts are caused by a failure to clear accumulating aggregated proteins in the lens. MicroRNAs are small non-coding transcripts which bind to specific mRNAs acting at...

AMD and visceral fat and pro-inflammatory factors

Several large studies have shown a positive relationship between age-related macular degeneration (ARMD) and high body mass index. The waist-hip ratio is also associated with development of early AMD. Visceral fat has a pro-inflammatory effect, which means it has an...

Detailed overview of diplopia causes and outcomes for a single tertiary care centre

The purpose of this study was to study the aetiology, progression and outcome in patients with binocular diplopia presenting to the ophthalmology department of a tertiary care centre in India. The study had a prospective observational design where all patients...

Function vision outcomes in pseudophakic children

This study evaluated the functional vision of 196 pseudophakic children and their carers treated at a tertiary centre in Southwest Nigeria and identified association factors. Mean age was 9.8 ±3.4 years (range 2–16) with 68.9% male and 31.1% female. Median...

Association of strabismus with functional impairment in children in the USA

In this study the authors aimed to (1) determine if strabismus is associated with clinically significant functional impairment, (2) identify specific domains of impairment and (3) examine predictors of impairment among children aged 5-17 years. Data were extracted and analysed...

Increase in myopia during the Covid-19 lockdown periods

The aim of this study was to examine the effect of the Covid-19-related lockdown on myopia progression of school-aged children in Lebanon. The authors reviewed 443 records of myopic children aged 3–18 years (mean 11.81 ±3.67) presenting from January 2020...

Iranian prevalence of amblyopia

This population-based study was conducted in the Mashhad County in the north east of Iran to determine the prevalence of amblyopia and its determinants and to predict the health needs of the county. This was a cross-sectional study and of...

Normative dimensions of the lacrimal gland

This article looks at the normative dimensions of the lacrimal gland in the axial and coronal plane on fat-suppressed T1 weighted contrast-enhanced magnetic resonance imaging (MRI). Previous data on this subject has come from computed tomography (CT). MRI is known...

Management of congenital NLD obstruction

The authors evaluated changes in management of congenital nasolacrimal duct obstruction (CNLDO) by surveying 1495 Association for Paediatric Ophthalmology & Strabismus (AAPOS) members. The survey consisted of 21 multiple choice questions with anonymised return. Responses were received from 127 members...

Outcomes for congenital vs. developmental cataract surgery

This study retrospectively reviewed follow-up data (minimum one year) to evaluate ocular outcomes and the potential factors affecting visual acuity after foldable intraocular lens (IOL) implantation in preschool childhood (up to six years) with bilateral cataract. The study included 43...

Germline mutation risk in solitary unilateral retinoblastoma

This study aimed to determine the true risk for germline mutation in a child presenting with solitary unilateral RB and whether this risk differs by age at presentation. This was a retrospective review of 482 cases from 1972-2020. Age groups...

Amblyopia risk factors with nasolacrimal duct obstruction in newborns

This study compares amblyopia risk factors in 1) newborns with congenital nasolacrimal duct obstruction (CNLDO) and age-matched healthy controls, 2) newborns with unilateral and bilateral CNLDO and 3) affected eye and fellow eye of newborns with unilateral CNLDO. The authors...