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1853 results found

Revision of orbital fracture repairs

This is a retrospective review of 13 patients with sub-optimal outcomes following primary orbital fracture repairs who underwent revision surgery. All had fractures of the orbital floor, with four involving other orbital walls, and six also involving other facial bones....

Lacrimal gland carcinoma

This is a major review of the management of lacrimal gland carcinoma, focusing mainly on adenoid cystic carcinoma. Relevant literature published in English since 1970 was included amounting to some 40 articles after filtering. Overall mortality for all lacrimal gland...

A comparative treatment study of VCZ and liposomal AmpB in an Aspergillus fumigatus endophthalmitis model

This study aims to compare the effects of voriconazole (VCZ) and liposomal amphotericin B (AmpB) in an experimental model of exogenous Aspergillus fumigatus endophthalmitis in a guinea pig animal model. Endophthalmitis was induced by intravitreal injection of a strain of...

Emergency eye care in the UK: the way forward?

In this paper the authors highlight issues pertaining to the growing number of patients presenting to the emergency eye services in the UK. Data collection involved literature review, telephone surveys and email correspondence (n=142). Ninety-one lead clinicians responded and a...

OCT measures of lateral and medial recti

The authors assessed the agreement of the measurements of the horizontal rectus muscle insertion distance to the limbus and the muscle thickness between three different OCT devices. This was a cross section observation study of 70 eyes of 35 subjects....

Phaco-ECP vs. Phaco alone to treat glaucoma

This retrospective review compared combined phacoemulsification and endoscopic cyclophotocoagulation (phaco-ECP) to phaco alone in patients with mild to moderate glaucoma. Outcome measures included cumulative full and qualified success survival, postintervention IOP and ocular anti-hypertensive medication reduction. Full success was defined...

LASEK with mitomycin C to correct myopia in thin corneas

This study evaluated the long-term outcomes of laser-assisted subepithelial keratomileusis (LASEK) with intraoperative use of mitomycin C (MMC) performed on thin corneas for the correction of myopia. MMC modulates the corneal wound healing response in surface healing, thus reducing the...

EDTA chelation for band keratopathy

The authors describe a retrospective analysis of 89 eyes from 72 patients who underwent ethlenediamine tetra-acetic acid (EDTA) chelation for band keratopathy. The ratio of R:L eye was 41:48. The mean age was 71 years (range 18-93 years). Thirty-two out...

Intravitreal injection related endophthalmitis

This article reviews the incidence, clinical findings, risk factors, management and visual outcomes in intravitreal injection related endophthalmitis. Incidence of this complication is reported to be in the range of 0.038% to 0.065% (1 in 2000-3000 injections). Patients present typically...

Ovarian hormones drive onset of Sjogren’s disease in mice

Sjogren’s syndrome (SS) is a debilitating, sight-threatening, systemic autoimmune disease with no effective treatment available. SS is characterised by lacrimal gland lymphocytic infiltration and epithelial cell death, as well as by the presence of serum autoantibodies. Patients have severe dry...

Direct endoscopic probing for congenital lacrimal duct obstruction

The most common treatment for congenital lacrimal duct obstruction (CLDO) is probing, which is traditionally a blind procedure. Previous literature reports success rates between 78-92%. The authors of this retrospective non comparative case series reviewed the success rates of probing...

New mouse model of diabetes mellitus

Diabetic retinopathy (DR) is a serious complication of diabetes. It is driven by the loss of pericytes, cells which control vascular function, due to excess formation of sugar alcohols by the enzyme aldose reductase (AR). AR has been shown to...