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3198 results found

Effect of preservative free fluoroquinolones on human corneal epithelial cells in vitro

Fluoroquinolones, including second generation (ofloxacin and ciprofloxacin), third generation (levofloxacin and tosufloxacin) and fourth generation (gatifloxacin and moxifloxacin), are a group of bactericidal agents used to treat multiple ocular infections. The third and fourth generation fluoroquinolones have enhanced Gram-positive activity...

The inflammatory side-effect of Brimonidine

Brimonidine is a well established selective alpha-2 adreno-receptor agonist, used to lower intraocular pressure. This case series reports on 19 eyes affected by brimonidine induced uveitis. Mean age of the patients was 74 years and mean duration of brimonidine use...

Medical treatment of orbital lymphatic malformations

This is a literature review of the use of Sirolimus, to treat orbital lymphatic malformations. Sirolimus is an immunosuppressant used in renal transplants, and acts by inhibiting mammalian target of rapamycin (mTOR), which in turn inhibits activation of T and...

Rituximab as an immunosuppression treatment for thyroid eye disease

Thyroid eye disease is traditionally treated with high dose glucocorticosteroids and surgical orbital decompression, where responses are often inadequate. This medical treatment is centred around symptom control and reduction of thyroid hormone synthesis, not immunosuppression. Rituximab is an anti-CD20 monoclonal...

CHEC Announces Collaboration with Award-winning Eyecare Company

Leading ophthalmologist Nikolina Budimlija to host CPD event in early October. Collaboration with family run Scope Eyecare reflects CHEC’s continued expansion of services and expertise.

Safe cataract extraction with underlying hypotonous cilio-choroidal detachment following trabeculectomy surgery

The authors of this study (including the reviewer of this article) describe a surgical technique for phacoemulsification in the presence of shallow choroidal detachment owing to hypotony following trabeculectomy. In their case series, four eyes of four patients with advanced...

Urban Changes and Rural Struggles for Ophthalmology in China

China is by far the most populated country in the world, with over 1.3 billion inhabitants. It is also the country with the highest number of blind and visually impaired people. As a developing country, half of China’s population lives...

Assessing everyday visual function in dry AMD – what matters to the person?

Age-related macular degeneration (AMD) is the primary cause of blindness in the developed world and is accountable for more than one half of sight impairment registrations within England and Wales [1]. AMD is prevalent in people aged 60 years and...

My Top Five: Emerging technologies revolutionising ophthalmology

Advancements in ophthalmology have significantly transformed eyecare practices. This article explores five emerging technologies that are revolutionising the field, from virtual reality (VR) surgical training to novel therapies for corneal conditions. These innovations are reshaping how eyecare professionals diagnose, treat...

A missed opportunity

Back in 2000 Sir Liam Donaldson wrote a piece of work commissioned by the then Secretary of State for Health entitled “An Organisation with a Memory”. We are now 18 years on and still some of the recommendations from them...

The ‘art’ of refraction – designing a refraction course

Learning how to refract requires theoretical knowledge, practice and determination. Refraction is a notoriously challenging skill to acquire and the competing demands on junior ophthalmologists can often be restrictive of the development of this core skill. To consolidate theory learnt...

Refractive changes after surgery

A long-term follow-up study was conducted to report power vector analysis of refractive astigmatic changes in a large group of 137 patients (250 eyes) undergoing horizontal strabismus surgery. Fifty-four percent were male. The average age was 9.22±8.21 years. Fifty-five percent...