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Regulatory drug evaluations and expedited review initiatives: EU and US perspectives
The European Medicines Agency (EMA) and United States Food and Drug Administration (FDA) each conduct independent assessments of benefit-risk profile when evaluating applications to market new or modified medicines, and their respective decision-making is guided by distinct legislation, procedures and...Addressing medical risk factors for diabetes and understanding the new systemic treatments
As global diabetes figures continue to rise, the importance of reducing the burden of macrovascular and microvascular complications of diabetes has never been so great. By 2025 it is estimated that five million people in the UK will have diabetes...Artificial intelligence could transform patient education in eyecare
A multilingual, voice-enabled chatbot helps patients access retinal detachment advice through personalised, real-time, clinically grounded conversations. From hospital leaflets to spoken answers in dozens of languages, new research from the University of East London (UEL) suggests artificial intelligence could dramatically...Telemedicine strategies in ophthalmology: harnessing established and emerging technologies for lasting solutions
The author considers recent progress and shares insights from leading practitioners in telemedicine applications and digital technology strategies. Amidst COVID-19 and combined mitigation and suppression measures, hospitals and clinics have responded rapidly to strengthen telemedicine strategies and virtual healthcare services...DMEK vs. UT-DSAEK: has the debate been finally concluded?
In recent years the surgical treatment of corneal endothelial dystrophy has progressed tremendously. Descemet’s membrane endothelial keratoplasty (DMEK) is the newest iteration in the line of rapid surgical advances that has taken place. However, the previously accepted gold standard prior...
Measuring IPD with PlusoptiX
The authors evaluated the accuracy of the PlusoptiX A04 for measuring pupillary distance as compared to measurements taken by a trained optician. This retrospective review included 256 children who had undilated PA04 screening and had pupil distance measurement done by...
Plusoptix referral criteria
The authors compared various referral criteria on the same group of patients to determine the sensitivity, specificity and predictive value of each. They also programmed the plusoptix to use the 2013 American Association for Pediatric Ophthalmology and Strabismus (AAPOS) referral...
Stereopsis changes with cataract
Stereoacuity was compared preoperatively to six weeks postoperative after cataract extraction and intraocular lens (IOL) implant. The authors evaluated the association of postoperative stereoacuity with visual acuity, age and duration of preoperative symptoms. This prospective study recruited 142 patients: 92...
Amblyopia OCT results
The authors compared the macular and peripapillary retinal nerve fibre layer (RNFL) thicknesses of amblyopic and fellow eyes using Stratus optical coherence tomography (OCT) to reveal any differences. They sought to determine the anatomical differences between these subtypes of strabismic...
Screening with PlusoptiX
This study compared the PlusoptiX A12 to a comprehensive ophthalmic investigation. This was a three-month study of 219 (438 eyes) subjects with a mean age of 72 months. The A12 referred 101 of 219 (46%) patients for potential amblyopia. Ophthalmic...
LASIK for myopia progression
The authors hypothesise that corneal reshaping with refractive surgery could have an effect on myopic progression similar to that of orthokeratology because it results in changes to the central cornea and not to the peripheral cornea. This was a retrospective...
