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PD-1 and PD-L1 in exenteration specimens
This is an immunohistochemical study looking at variation in the expression of the programmed death-1 receptor (PD-1) and the programmed cell death ligand-1 (PD-L1), comparing cutaneous malignancies which invaded the orbit with uncomplicated nodular basal cell carcinomas. The authors retrospectively...
Pterygium ocular surface temperature
This prospective study investigated the ocular surface temperature in patients with pterygia compared to those with dry and healthy eyes respectively. Previous studies have shown that patients with dry eyes show a significant decrease in ocular surface temperature on sustained...
Reduced blood flow and age-related macular degeneration
This was a prospective cross-sectional study assessing changes in blood flow velocity in patients with age-related macular degeneration (AMD) using a retinal function imager. Sixty eyes with wet AMD were compared to 53 control eyes and the average blood flow...
Complement factor B polymorphism and the phenotype of early age-related macular degeneration
The relationship between complement factor H (CFH) and age-related macular degeneration (AMD) is very well known, but other genetic polymorphisms relating to AMD are more poorly understood. This study was designed to investigate the relationship between complement factor B (CFB)...
Topical doxycycline for corneal neovascularisation
Six eyes with corneal vascularisation were treated with 1% topical doxycycline, four times a day for three weeks. The patients were reviewed at various intervals over a period of one year. The eyes selected had neovascularisation secondary to a variety...
Canaloplasty after failed trabeculectomy
The authors describe the technique of canaloplasty performed in five patients who had undergone previous trabeculectomy and under maximum tolerated medical therapy or insufficient intraocular pressure (IOP) control. Canaloplasty is described by the authors as “a nonperforating blebless technique derived...
A relationship between central serous retinopathy and obstructive sleep apnoea
This prospective study aimed to evaluate a relationship between central serous retinopathy (CSR) and obstructive sleep apnoea (OSA). Twenty-three subjects (six female and 17 male) were diagnosed with CSR and overnight polysonography was performed to record desaturation and apnoeic episodes....
A case report of cavernous sinus syndrome following dental procedure
This case report describes a patient presenting with painful diplopia as a consequence of root canal dental treatment. Following root canal treatment a non-resolving tooth pain led to a decision to extract the tooth, leading to onset of severe periorbital...
Open-field autorefraction screening
This study aimed to determine the efficacy of the Shin-Nippon NVision-K5001 autorefractometer using the open-field refractometry principle in the elimination of accommodation in children. One hundred and fourteen patients aged three to six years were recruited. After excluding ocular pathology...
Visual outcomes, visual fields and optical coherence tomography in paediatric craniopharyngioma
This study reviews the visual outcomes of ten patients under the age of 18 years with craniopharyngioma. The paper also reviews the correlation between visual field (VF) testing and optical coherence tomography (OCT) examination and evaluates the role of OCT...
Lower postoperative scar height is associated with increased postoperative trichiasis one year after bilamellar tarsal rotation surgery
Bilamellar tarsal rotation has been a key component of the WHO SAFE approach to blindness from trichiaisis (surgery, antibiotics, facial hygiene, environment). The World Health Organisation (WHO) manual describes the procedure as a full thickness blepharotomy placed 3.0mm above and...
