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Complement factor B polymorphism and the phenotype of early age-related macular degeneration

1 August 2014 | | EYE - Vitreo-Retinal
The relationship between complement factor H (CFH) and age-related macular degeneration (AMD) is very well known, but other genetic polymorphisms relating to AMD are more poorly understood. This study was designed to investigate the relationship between complement factor B (CFB)...

Complement Factor H and Factor H-Like protein are expressed in human RPE cells

1 April 2014 | | EYE - General
The role of inflammation in age-related macular degeneration (AMD) is well documented and the association of AMD with the inflammatory marker C-reactive protein (CRP) and members of the complement system underline the role of complements in AMD. Human complement factor...

The rarebit vision test for macular conditions

1 October 2015 | | EYE - Vitreo-Retinal
Rarebit testing is used to measure low degrees of neuro-visual damage and is available for free on the internet. It consists of a fixed bright light dot presented on a black background. During testing it is presented briefly at different...

HtrA1 enhances cell senescence

1 December 2013 | | EYE - Vitreo-Retinal
A genetic basis for age-related macular degeneration (AMD) has been greatly advanced in recent years. The role of identified pathways such as complement factor H in AMD has been widely investigated. However, the effect of other gene variants identified by...

Discussing treatment modalities for bilateral wet AMD

1 December 2014 | | EYE - Vitreo-Retinal
A 65-year-old lady with bilateral wet AMD and vision of 6/24 comes with an internet search about current therapies. How do you explain the various treatment modalities available? There are two NICE approved treatments for wet age-related macular degeneration (AMD)....

Transfected RPE cells inhibit AMD in rats

1 August 2015 | | EYE - Vitreo-Retinal
Age-related macular degeneration (AMD) is a leading cause of blindness in the elderly. Wet AMD is characterised by choroidal neovascularisation, new vessels into the retina, leading to leakage and tissue damage. Many proangiogenic factors particularly vascular endothelial growth factor (VEGF)...

Coming to terms with AI

1 August 2019 | | EYE - Imaging, EYE - Vitreo-Retinal, EYE - Glaucoma, EYE - General
A machine might be called intelligent if its response to questions could convince a person that it was human, a test proposed by Alan Turing in 1950 [1]. The author considers potential applications of artificial intelligence (AI) using machine learning...

What’s new in wet AMD papers?

1 December 2016 | | EYE - Vitreo-Retinal
Paper presentations on neovascular (‘wet’) age-related macular degeneration (AMD) from the 16th European Society of Retina Specialists Congress, Copenhagen, September 2016, outline recent research directions evaluating the impact of vision loss on key health domains, patient preferences in the process...

Patients blinded by stem cells! How safe are they really?

1 October 2018 | | EYE - Vitreo-Retinal, EYE - General
Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are based on facts and which are ‘fake news’. Headline: Patients blinded by stem cells! How safe are they really? Ever since the successful results following...

Guilty till proven otherwise! @ 100% Ophthalmology

25 February 2024
@10:15 – 11:15 Picture quiz on eyelid tumours.

AI in anterior segment disease - what you need to know! @ 100% Ophthalmology

25 February 2024
@11:30 – 12:30 Everything you need to understand before you start to consider using AI in your practice with a focus on anterior segment disease!

Handheld OCT in children @ 100% Ophthalmology

25 February 2024
@12:45 – 13:45 This session will provide an exciting overview of handheld OCT applications in children, relevant to a general audience. This will include clinical applications across numerous conditions, tips for successful image acquisition, and research updates.