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Understanding amniotic membrane grafts

Safa Elhassan gives a brief review of amniotic membrane grafts and their application in theatre and clinic-based settings. Amniotic membrane (AM) transplant has been an established adjuvant treatment for many corneal, conjunctival and scleral disorders in ophthalmic clinical practice with...

Proning and the pandemic - ocular complications seen in critical care

Priyanka Sanghi and her co-authors explore the ocular complications seen in critical care units throughout the country as we treat patients through this challenging time. The SARS-Cov-2 (COVID-19) pandemic has placed the NHS and critical care services under immense strain,...

Genetic profiling for personalised healthcare solutions in AMD – an update

Age-related macular degeneration (AMD) is a multifactorial condition influenced by genetics and lifestyle factors (Table 1). This article outlines several recent advances in AMD genetics, as well as evolving therapeutic concepts and established practical measures for the treatment and /...

Multidrug-resistant keratitis: challenging yet manageable

This is a retrospective review of all patients’ records from a tertiary referral centre in India from January 2018 to December 2019, who had corneal scrapings for direct smear and culture sensitivity. Those cases where the organisms were diagnosed to...

CD40L activation of human RPE cells

Age-related macular degeneration (AMD) is the leading cause of reduced visual acuity in the elderly worldwide. The risk factors involved in AMD include smoking and diet, while genetics have been shown to have a significant role. Recently a link between...

Choroidal and RNFL thickness in patients with OSAS

In obstructive sleep apnoea syndrome (OSAS), hypoxia secondary to repetitive apnoeic episodes leads to blood pressure variations and haemodynamic changes. There is also intermittent activation of the sympathetic system when the patient is aroused from sleep during apnoeic episodes. OSAS...

Discussing treatment modalities for bilateral wet AMD

A 65-year-old lady with bilateral wet AMD and vision of 6/24 comes with an internet search about current therapies. How do you explain the various treatment modalities available? There are two NICE approved treatments for wet age-related macular degeneration (AMD)....

In conversation with Professor Usha Chakravarthy (2018)

Professor Chakravarthy popped by the Eye News stand at the 2018 Royal College of Ophthalmologists Annual Congress after her excellent Bowman Lecture. She gave us a summary of her presentation, which looked at how our understanding of AMD has changed...

Investigating the link between corneal clarity and statin use

Transparency is a vital attribute of the cornea, necessary in preserving healthy vision. Maintaining this requires the collective input of the various layers of the cornea. Mostly, the layers implicated in this are the corneal stroma and endothelium [1]. Our...

The management of possibly progressive pterygium

A 43-year-old Sudanese male patient is referred by his GP with a fleshy lesion encroaching the nasal cornea for the last six months. History Make note of: risk factors, i.e. UV exposure and ocular irritation - history of living in...

My top five: Innovative approaches to dry AMD

Age-related macular degeneration (AMD) is one of the leading causes of irreversible blindness in the developing world with its prevalence rising alongside age. In societies characterised by ageing populations, it is imperative we explore more effective treatment to alleviate the...