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A rare case of bilateral multifocal vitelliform dystrophy

Vitelliform macular dystrophies are a subset of retinal dystrophies that result in the accumulation of lipofuscin, commonly in the macula leading to the formation of characteristic vitelliform lesions [1]. Most cases have a solitary lesion in the macula, but rarely...

The most memorable patient encounters and what they taught me

In ophthalmology, some encounters blend quietly into the rhythm of clinic. Others stay with us, shaping how we practice and who we become as clinicians. These moments become the unexpected teachers of our training. They are subtle yet leave a...

Management of proliferative diabetic retinopathy

Diabetic retinopathy is a major cause of blindness in the working-age population. Due to the worsening global epidemic of diabetes, the incidence of morbidity caused by the disease is set to increase [1]. The prevalence of diabetes in the UK...

ESASO Course Series Vol. 4 Optical Coherence Tomography

This book, which is the latest volume from the European School for Advanced Studies in Ophthalmology (ESASO) course series, is a revelation and joy to review. This compact volume provides an introduction and an update to the most recent technological...

HLA-B27 anterior uveitis

HLA-B27 has previously been shown to have an association with uveitis, ankylosing spondylitis, reactive arthritis, ulcerative colitis and psoriasis. The authors of this review provide an update of the epidemiology of HLA-B27 associated ocular disorders. There is great variation amongst...

A review of chromosome 9p21 POAG susceptibility locus

Primary open angle glaucoma (POAG) is a genetically complex disease and the overall phenotype is influenced by multiple traits including intraocular pressure (IOP), central corneal thickness and structural features of the optic nerve head. Therefore, genes affecting any of these...

A comparison of colour vision tests in the presence of contrast sensitivity loss

This study analyses the effect of contrast sensitivity (CS) loss on colour vision (CV) testing, using a variety of colour vision tests. The authors used a computer model for CS loss to determine its effect on CV testing scores for...

Do bilateral same day intravitreal injections increase the risk of endophthalmitis?

This large retrospective cohort study reviewed all patients who had bilateral intravitreal anti-vascular endothelial growth factor (VEGF) injections between April 2012 and August 2017. There were 101,932 procedures performed in 5890 patients. The two most common indications for injections were...

Is pre-eclampsia / eclampsia a risk factor for non-infective uveitis?

This population based retrospective matched cohort study was the first of its kind to suggest an association between preeclampsia / eclampsia (PEE) and non-infective uveitis (NIU). They used the Longitudinal National Health Insurance database in Taiwan to assess 2073 post-delivery...

Myopia rate of change from 5-20 years

Data was collected from the 2008-12 KNHANES survey and the study included 7695 of 9351 subjects with refractive data. The mean age was 11.8 years (5-20 range) with 48.2% female. Mean spherical equivalent was -1.82 ±2.23D. For five-year-olds, the mean...

Parent-reported outcomes after cerebral hemispherectomy

The authors present the findings of a survey circulated by the Childhood Epilepsy Surgery Foundation to its members. Parents of children who had undergone a cerebral hemispherectomy were invited to participate. A total of 48 responses from 248 who were...

Diagnostic accuracy of different keratoconus detection indices of pentacam in paediatric eyes

This is a retrospective study of 432 non-keratoconic eyes compared with 48 eyes with keratoconus (KC) or forme fruste KC (FFKC) in a paediatric population in Cairo, Egypt between December 2013 and October 2018. The authors discuss the rationale of...