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CRATER 2025

The Conference on Recent Advances in Translational Eye Research 2025

World-class centre for eye health reaches construction milestone

The new home for Moorfields Eye Hospital NHS Foundation Trust and the UCL Institute of Ophthalmology reached a significant construction milestone today. The completion of the concrete structure as part of the new centre for advancing eye health in St...

New solutions in the prevention and treatment of Acanthamoeba keratitis

The global increase in Acanthamoeba keratitis infections has emphasised the inefficiencies of current treatment and preventative methods, here researchers from the West of Scotland detail a promising new series of compounds that may stem the tide. News headlines detailing horror...

Propranolol treatment of infantile haemangioma

This is a retrospective review of 104 patients treated for infantile haemangioma between January 2009 and July 2012. All patients underwent pretesting either with protocol A (administration of test dose with routine observations) or protocol B (cardiology clinic assessment, including...

A case report of alternating anisocoria with associated nasal congestion

The authors have described a group of healthy individuals who show alternating anisocoria, in a previous paper. In these cases, the pupil asymmetry alternates between eyes every few hours, with no observed instances when both pupils are equal in size....

VEGF and axial length (RVU)

The authors of this paper set out to examine whether the concentrations of VEGF in the vitreous were associated with refractive error and axial length in eyes without retinal disease, except of macular holes or epiretinal membranes. A vitreous sample...

Screening for stroke-related visual problems

The aim was to report the initial development and evaluation of a suitable screening tool for detecting visual problems after stroke. The tool has four components. The first three include questions asked by examiners about patients’ ocular history and symptoms,...

Effect of refractive corneal surgery on IOP and glaucoma progression

Accuracy of intraocular pressure (IOP) measurement depends on the biomechanical properties of the cornea, including its thickness central corneal thickness (CCT) and keratometry (K). Fifty-six eyes of 56 patients with primary open angle glaucoma (POAG) who had a history of...

Screening accuracy

In this study the authors observed whether and how well orthoptic tests are performed by non-orthoptists in a screening setting. They assessed the quality of screening tests by semi-structured observations of youth health care (YHC) physicians who screened children aged...

Cystoid macular oedema following cataract surgery

This review covers the history, incidence, diagnosis, risk factors, pathophysiology and medical management of postoperative macular oedema (PCMO), with a particular emphasis on key contemporary studies and novel observations. The authors revisit the incidence of well-established risk factors including intraoperative...

Variability and reliability of Lea grating paddles

The authors aimed to determine interobserver variability and reliability of Lea grating paddles when assessing grating acuity in pre and non-verbal children. This was a prospective study of 31 consecutive patients; 29 pre-verbal <36 months and two with delayed speech...

Case reports of ‘ictal lid saccades’ and ‘ictal blinks’

The authors present two cases of lid movements with discrete physiology and propose the terms ‘ictal lid saccades’ and ‘ictal blink’ to describe the movements seen. These two types of lid movement, blinks and saccades, have discrete kinematic properties and...