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Characteristics of limbal lymphatic vasculature on confocal microscopy

This ex vivo study aims to describe the morphological characteristics of the human limbal lymphatic vasculature using confocal microscopy and immunofluorescence. Twelve corneal specimens are obtained from human donor eyes. These corneal buttons are not suitable for transplantation due to...

Review of pathogenesis of Acanthamoeba keratitis

In this review, the author summarised the current microbiomic and immunological evidence related to the pathogenesis of Acanthamoeba keratitis (AK). AK has been described for almost 50 years, but the exact biology of the disease remains perplexing. Acanthamoeba spp. are...

Mobile phone use with esotropia development

This study analysed clinical characteristics and surgical outcomes in patients with acquired comitant esotropia (ACET) and determined the prevalence of excessive mobile touch screen device use in these patients. This was a retrospective study of 35 patients of which three...

Transient macular thinning with Densiron 68

Densiron 68 is a heavy silicone oil (HSO) used to treat rhegmatogenous retinal detachments (RRD) with inferior retinal breaks. The authors compared changes in retinal thickness during and after the use of Densiron endotamponade, and looked at any association between...

Sarcoid uveitis and its systemic associations

This retrospective cross-sectional study examined systemic associations of sarcoid uveitis and association with uveitis clinical phenotype and ethnicity. Three hundred and sixty-two subjects with either definite or presumed sarcoid uveitis were identified and included in the study. Any subject with...

Inflammation and microvascular changes in diabetic retinopathy

Studies have shown that neurodegeneration and inflammation in the retina start early in diabetic retinopathy (DR) and can be present before the latter is clinically evident. The aim of this retrospective review of 99 diabetic patients was to evaluate retinal...

Assessment of slow and fast vergence in stroke survivors

The authors present the findings of a prospective cohort study. Three hundred and five stroke survivors were recruited consecutively. The following exclusion criteria were applied; aphasia, cognitive impairment, visual inattention, ocular motor nerve palsy and neuromuscular disease. Fifty age-matched controls...

Significant associations to presence of significant retinal haemorrhages in suspected child abuse

The authors aimed to extract statistically significant associations between non-ocular clinical and diagnostic imaging findings and the presence of significant retinal haemorrhages, and then develop an evidence-based screening algorithm to determine when to consult an ophthalmologist in suspected child abuse...

How long to wait to refract after instilling cyclo drops for children with brown irides?

This study aimed to assess the time needed for effective cycloplegia after instillation of 1% cyclopentolate drops in children with brown irides. The study recruited 161 consecutive patients aged three to 16 years. All had refraction on arrival, then instillation...

Use of international interocular difference thresholds for optic neuritis diagnosis in clinical practice

Multiple sclerosis (MS) is the most common non-traumatic cause of disability in young people, and visual symptoms can be the initial manifestation in up to 20% of cases. Retinal examination can be helpful in making the correct diagnosis. The latest...

Higher risk of poor functional outcome in the presence of visual deficits post-stroke

The authors present a retrospective case review with the aim of reporting the disability outcomes of individuals 90-days post stroke with and without visual deficits. The Houston Methodist Hospital Outcomes-based Prospective Endpoints in Stroke (HOPES) Registry was used as the...

Risk factors identified for glaucoma progression in paediatric glaucoma suspects

A retrospective case review was conducted of children (<18 years) identified as being glaucoma suspects using common clinical criteria or the Childhood Glaucoma Research Network definition. Exclusion criteria included penetrating ocular trauma, treated ocular hypertension / glaucoma and use of...