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SOS (Simplified Ophthalmic Statistics) Part 3: Which statistical test should I use (if any)?
P<0.05 is a statement that brings joy to many researchers. Arguably this is because inclusion of such a statement may increase the chance of acceptance for publication. Whilst statisticians and non-statisticians are united in trying to change this culture, cultural...Conference Report: ARVO 2025 Annual Meeting
The Association for Research in Vision and Ophthalmology (ARVO) 2025 Annual Meeting was held at the Salt Palace Convention Centre in Salt Lake City, US. This prestigious event brought together experts in vision and ophthalmology from around the world for...Kabgayi International Ophthalmology Conference 2024
by Michael Mikhail, FRCOphth, Consultant Ophthalmologist; Vitreoretinal Surgeon, Kabgayi Eye Unit, Rwanda. My journey to Rwanda in April 2022 aimed to expand vitreoretinal services, but it also highlighted the need for robust scientific discourse, akin to the UK's ophthalmology culture,...
Achieving post-op target range increases success of strabismus surgery in adults
This is a retrospective cohort study of all patients over 12-years old undergoing strabismus surgery under a single surgeon in a tertiary referral centre in Toronto, Canada. The aim of the study is to determine the role of achieving immediate...
Aflibercept treatment in polypoidal choroidal vasculopathy
The authors present a study to evaluate the anatomical and functional efficacy of aflibercept intravitreal (IVT) as a monotherapy in polypoidal choroidal vasculopathy (PCV) in a Caucasian population treated with initial three-monthly aflibercept IVT, followed by a bimonthly regimen for...
Transient thickening of the macular retinal nerve fibre layer in acute optic neuritis
Acute optic neuritis (ON) causes axonal degeneration, which can be quantified from the blood by neurofilament protein (Nf) levels. Within about three months, atrophy of the retinal nerve fibre layer (RNFL) follows. However, it remains challenging to explain why there...
Patterns of binocular diplopia in giant cell arteritis (GCA)
Giant cell arteritis (GCA) is a granulomatous vasculitis that targets medium and large sized vessels. Binocular diplopia has been reported in a small number of patients with visual manifestations of GCA. It can be caused by ischaemia in any segment...
Intravitreal dexamethasone in diabetic macular oedema (DMO) - enhancing the response to anti-VEGF in non- or poor responders
This study aimed to describe the outcomes of a switch back from DEXi (dexamethasone implant) to anti-VEGF therapy in eyes that were treated temporarily with DEXi after an initial poor response to anti VEGF. Twenty-three eyes of 17 patients were...
