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Do patients with prolactinomas using dopamine agonist drugs have autonomic dysfunction?

This prospective study aimed to determine whether there is autonomic dysfunction in patients with prolactinomas using dopamine agonist (DA) drugs by measuring static and dynamic pupillary responses using an automatic pupillometric device.Included were 25 eyes from 25 patients who were...

Differences in elastometry of cornea and optic nerve head in both eyes of patients with NAION

Non-arteritic anterior ischaemic optic neuropathy (NAION) is an important cause of visual loss in the middle aged and elderly population. This prospective cross-sectional study investigates the biomechanical properties of optic nerve head (ONH) and cornea in both eyes of patients...

A retrospective medical notes review in patients with poor vision due to NAION

Very severe visual loss (hand movements or less) is typical of arteritic anterior ischaemic optic neuropathy (AION) and relatively rare in non-arteritic AION (NAION). This study aimed to report the frequency of very poor visual acuity (VA) in NAION. The...

Intravitreal bevacizumab vs. triamcinolone in patients with DMO at the time of cataract surgery

This prospective, single masked randomised control trial (RCT) compared visual and anatomical outcomes when either intravitreal bevacizumab (BVB) or triamcinolone (TA) was administered at the time of cataract surgery and at subsequent review, if required, in patients with diabetic macula...

Injection frequency and anatomic outcomes following conversion to Aflibercept in neovascular AMD patients

This is a retrospective study of patients with neovascular age-related macular degeneration (AMD) treated with intravitreal Lucentis and / or Avastin who were switched to aflibercept (Eylea). This study was carried out by the Casey Eye Institute retinal clinics, between...

Lens surgery in patients with lens subluxation misdiagnosed as primary angle-closure glaucoma

Lens subluxation can be caused by many conditions including Marfan syndrome and other hereditary conditions, and blunt trauma. Lens displacement can cause pupillary block and angle closure. This is commonly misdiagnosed as primary angle closure glaucoma (PACG), which can lead...

OCT prognostic factors in AMD patients with peripapillary choroidal neovascularisation

In this retrospective study the authors aimed to investigate the correlation between optical coherence tomography (OCT) findings and visual acuity outcomes after treatment with intravitreal bevacizumab (IVB) injections for age-related macular degeneration (AMD) patients with peripapillary choroidal neovascularisation (PPCNV). Data...

Comparison of false-negative responses in glaucoma patients and normal observers

The authors compared false negative rates for full threshold (FULL) and Swedish Interactive Threshold Algorithm (SITA) standard automated perimetry in healthy control subjects and glaucoma patients. Twenty-four subjects underwent visual field testing of one eye five times within six weeks...

Are any precautions needed when performing cataract surgery in thrombocytopenic patients?

In this retrospective multi-centre study, charts for 196 eyes of 150 thrombocytopenic patients were reviewed. The mean preoperative platelet level was 73.0 ± 20.5 × 103/μL (median of 76.0 × 103/μL), with a range of 17 to 100 × 103/μL...

Prognostic factors for visual acuity in patients with LHON after gene therapy

This retrospective study investigates prognostic factors affecting the visual acuity after a single intravitreal injection of rAAV2-ND4 gene therapy in 53 patients with Leber’s hereditary optic neuropathy (LHON) with mutation at site 11 778. Patients were reviewed one and three...

Intravitreal Bevacizumab for the prevention of postoperative proliferative vitreoretinopathy in high-risk patients

This single- centre observational retrospective study was conducted to evaluate the effect of intravitreal injection of bevacizumab at the time surgery for rhegmatogenous retinal detachment (RRD) repair on postoperative proliferative vitreoretinopathy (PVR) in patients at high risk selected by laser...