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The long-term effects of AREDS on AMD progression

The Age-Related Eye Disease Study (AREDS) was an 11-centre, double-masked, clinical trial that in 2001 found a high-dose of antioxidant vitamins plus zinc was effective in protecting against progression of age-related macular degeneration (AMD) in patients with moderate to high...

Macular pigment in relatives of AMD patients

Blue light causes photo-oxidative retinal injury and macular pigment (MP), with lutein, zeaxanthin and mesozeaxanthin as the main components, as a filter that protects the macula from this damage. Previous studies indicated that low levels of macular pigment optical density...

What's trending Feb/Mar 2023

A round-up of the eye related hot topics that have been trending on social media over the last few weeks. #nativity #needleeye Happy New Year! Let’s kick things off with a holiday-related story. Birmingham-based micro-engraver Graham Short engraved by hand...

Belfast briefing: Retina Day roundup from the RCOphth 2024 Annual Congress

Belfast hosted this year’s Royal College of Ophthalmologists’ (RCOphth) Annual Congress, a meeting dedicated to sharing advances, knowledge and clinical practice points in ophthalmic care. This article summarises selected talks by medical and surgical retina specialists during the Retina Subspecialty...

CD40L activation of human RPE cells

Age-related macular degeneration (AMD) is the leading cause of reduced visual acuity in the elderly worldwide. The risk factors involved in AMD include smoking and diet, while genetics have been shown to have a significant role. Recently a link between...

General purpose AI: Transitioning from high performance in highly curated settings to useful applications in ophthalmology

Artificial intelligence (AI) may be understood as the ability of machines to perform tasks which otherwise require human perception, reasoning, or learning. With the advent of deep learning, AI has achieved remarkable results across a wide range of medical tasks...

ILM peeling in primary rhegmatogenous retinal detachment

This author retrospectively analysed the correlation between internal limiting membrane (ILM) peeling and the occurrence of a postoperative epiretinal membrane (ERM) in patients who underwent vitrectomy for rhegmatogenous retinal detachment (RD). There were 135 medical records investigated. Seventy patients underwent...

Control of bleeding with diabetic vitrectomy under air

The authors describe a modified diabetic vitrectomy using continuous air infusion in diabetic eyes with severe fibrovascular proliferation. In their case series of 25 eyes (20 patients), intravitreal bevacizumab (1.25mg) was used one week prior to surgery. Fifteen eyes had...

2024

Welcome to our Spring Special of 2024! The year is well underway and I can feel change is in the air. It’s the Chinese year of the dragon, generally regarded as a good sign, plus it’s 40 years on from...

EDI (equity, inclusion and diversity) presentation @ 100% Ophthalmology

@14:00 – 15:00 Evelyn Mensah, Consultant Ophthalmologist - NHS Trust

Computerised visual acuity measurements in AMD

The aims of this study were to investigate whether half-letter width spacing in COMPlog algorithms had an adverse effect on agreement in patients with AMD with the ETDRS chart. Fifty adult participants with AMD took part with a median age...

AMD and visceral fat and pro-inflammatory factors

Several large studies have shown a positive relationship between age-related macular degeneration (ARMD) and high body mass index. The waist-hip ratio is also associated with development of early AMD. Visceral fat has a pro-inflammatory effect, which means it has an...