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Emerging therapies for geographic atrophy: complement inhibitors show potential to slow progression and preserve RPE and photoreceptor integrity

5 June 2023 |
Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD) characterised by progressive, irreversible loss of the retinal pigment epithelium (RPE) and photoreceptors and is estimated to account for approximately 10% of AMD-related blindness [1-4]. The Age-Related Eye...

Early vitrectomy for endophthalmitis offers hope to patients

4 August 2026 | research, treatment
A Phase 2 feasibility study published today in the prestigious Nature Communications Medicine journal has shown that early vitrectomy surgery treatment for acute endophthalmitis can be potentially more beneficial to patients’ vision compared with the current antibiotic-first approach. This is...

Letter from America: Orbit and oculoplastic fellowship, University of California, San Diego

1 June 2014 | | EYE - Oculoplastic, EYE - Orbit
I was the fortunate recipient of the 2012 Keeler Scholarship, granting me the incredible opportunity to undertake a fellowship at the University of California, San Diego (UCSD) in orbital, oculoplastic and reconstructive surgery. My fellowship mentors were the renowned Professor...
Image of the JAMA Network Reader.

Do topical steroids improve visual outcome in the treatment of bacterial keratitis?

1 December 2014 | | EYE - Cornea, EYE - General
The use of topical corticosteroids as an adjunctive treatment to antibiotics in the management of bacterial keratitis remains a controversial issue. The results of the Steroids for Corneal Ulcers Trial (SCUT) – a randomised, double-masked, placebo-controlled trial that recruited patients...
Cornea journal cover image.

Outcomes of corneal collagen crosslinking (CXL) in pseudophakic bullous keratopathy (PBK)

1 August 2014 | | EYE - Cornea, EYE - General
This was a retrospective non-comparative, interventional case series of 50 eyes in 50 patients with symptomatic PBK who underwent CXL (epithelium-off). Central corneal thickness (CCT), pain score, best corrected visual acuity (BCVA), and corneal transparency were recorded at baseline; at...

Foundation Post in Ophthalmology

7 February 2023 | | EYE - General
If you are in your final year of medicine at university, firstly congratulations on making it so far and secondly, you may be wondering how and which jobs to rank highly. If you have found yourself reading this article, then...

Ophthalmic Aid to Eastern Europe (OAEE)

4 March 2022 | | EYE - General
Peter Cackett, Tim ffytche and Dr Irina Gout reflect on historic ophthalmic aid sent to Eastern Europe. This article was written prior to the horrific events in Ukraine. An appeal for funds and equipment may be made by OAEE later...

Bilateral eye pain after contact lens wear: an inadvertent case of chemical eye injury

1 December 2022 | | EYE - General
Introduction There are around 4.1 million contact lens wearers in the UK [1]. While the vast majority of them do not experience any complications, over the past years there have been cases of acanthamoeba keratitis and multiple retained contact lenses...

Ophthalmology specialty training applications: a costly affair?

23 August 2021 | | EYE - General
Ophthalmology is one of the most competitive specialties to pursue training in worldwide. In the United Kingdom, the ST1 entry national selection competition ratio for the past few years has ranged between four to five applicants per post [1]. The...

Transferring imaging from primary to secondary care (part 1)

5 August 2020 | | EYE - General
Transferring clinical imaging from high street optometrists to secondary care is an increasingly requested option, especially in the context of the COVID-19 pandemic. A wide variety of solutions exist to allow this, each with their own merits and shortcomings. For...

Revolutionising eyecare: Gloucestershire’s Community Ophthalmic Link delivers nationally significant results

7 July 2026 | | EYE - Imaging
Ophthalmology is the largest outpatient specialty in the NHS, and in Gloucestershire, it is growing at an annual rate of 2.55%, outpacing other specialties. However, rising demand has led to significant waiting lists, often resulting in patients not being seen...

Quiz Jun/Jul 2024

3 June 2024 | | EYE - Oncology, EYE - Paediatrics, EYE - Strabismus, EYE - Pathology, EYE - General
History A one-year-old girl originally presented with a red eye, initially bilaterally and later in the left only. On examination a membrane was found on the tarsal conjunctiva of the upper eyelid (Figure 1). Figure 1: Anterior segment. Serum plasminogen...