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Moxifloxacin 0.5% for bacterial keratitis

The authors report on the results of a randomised controlled trial comparing commercially available non-preserved moxifloxacin 0.5% vs. a combination of fortified cefazolin 5% and tobramycin 1.3% in the treatment of moderate bacterial keratitis without perforation. Corneal scrapings were collected...

Delayed improvement in Muller’s muscle ptosis surgery

This is a retrospective review of patients undergoing ptosis surgery. The authors had noticed anecdotally that although a posterior approach Muller’s muscle and conjunctival resection (MMCR) appeared to achieve similar results to an anterior approach levator resection (ALR) in the...

Temporal versus nasal clear corneal incisions

This is a prospective randomised study of 100 patients’ left eye having undergone phacoemulsification either by a 2.4mm nasal clear corneal incision (CCI) group or temporal CCI group. The corneal astigmatic changes were compared between groups by power vector analysis,...

Lacrimal gland carcinoma outcomes

This is retrospective review of outcomes of lacrimal gland epithelial tumours treated between 1972 and 2014 at Moorfields Eye Hospital. Seventy-nine patients were reported, comprising 53 adenoid cystic carcinomas, 15 primary adenocarcinomas and 11 carcinomas ex-pleomorphic adenoma. The authors compare...

Neurofibromatosis type 1 features

The aim in this study was to identify the incidence and de nova mutation rate of Neurofibramatosis type 1 (NF1) and describe the ocular and non-ocular findings in a population-based cohort of patients diagnosed over a 30-year period. The study...

Orbital sphenoid sinus trauma: a rare trauma case

With a high complication and mortality rate, intra-sphenoidal and transorbital trauma poses a high complication rate and remains challenging to manage. Numerous key structures run nearby such as: the optic nerve, internal carotid arteries and ophthalmic arteries. The authors present...

OCT angiography sign after whiplash

Berlin’s oedema is a rare condition following blunt ocular injury and a rare finding after whiplash injury. This case describes a 48-year-old male who suffered a seventh vertebrae fracture from a traffic accident. Two days later, decreased left eye visual...

Intravitreal Ziv-Aflibercept: safety analysis

Ziv-Aflibercept (Zaltrap; Sanofi-Aventis U.S LLS, Bridgewater, NJ) was originally introduced as an intravenous formulation for metastatic colorectal cancer. The adoption of Ziv-Aflibercept in ophthalmic practice was similar to bevacizumab, and reports have previously examined one to two year visual outcomes...

Quality of life after oculoplastic surgery

This is a literature review of published quality of life surveys in patients who have undergone a variety of oculoplastic procedures. The authors emphasise the importance of patient reported outcomes, noting that clinician and patient perceptions may differ, and that...

Outcomes of early versus late surgery for infantile esotropia

The authors aimed to provide a better understanding of the clinical spectrum of infantile esotropia by comparing motor and sensory results in the long-term follow-up of patients who underwent surgery. This was a retrospective review over a 17-year period. There...

Efficacy and safety of novel PF brimonidine / timolol fixed-combination ophthalmic solution for OAG

This study is a multicentre, randomised, open-label, parallel-group clinical trial to evaluate the efficacy and safety of a newly developed preservative-free (PF) brimonidine / timolol fixed-combination (BTFC) ophthalmic solutions as compared with preservative-containing (PC) BTFC ophthalmic solution in adult patients...

Inflammation and microvascular changes in diabetic retinopathy

Studies have shown that neurodegeneration and inflammation in the retina start early in diabetic retinopathy (DR) and can be present before the latter is clinically evident. The aim of this retrospective review of 99 diabetic patients was to evaluate retinal...